Humans have long been familiar with narcotics. Modern life has paved the way for this familiarity to become a crisis that now considered a major health problem. Addiction is a serious, profound, and comprehensive problem that is the focus of various sciences, and substance abuse has considered as a disorder in psychology. Substance abuse disorder is one of the abnormalities that many efforts have made by various departments to treat. Opioid dependence refers to a set of physiological, cognitive, and behavioral symptoms that collectively indicate continued use of opioids despite severe problems resulting from their use. The male-to-female ratio is about 3:1, and opioid users generally begin using drugs in adolescence and early adulthood.
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