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Il carbazolo e i suoi composti ibridi sono stati considerati un tipo molto significativo di composti eterociclici contenenti azoto, abbondanti in natura. La parte carbazolica è il componente di molte sostanze biologicamente attive presenti in natura, come le murrayafoline e le carbazomicine. Numerosi composti carbazolici come ossazinocarbazoli, benzocarbazoli, piridocarbazoli, tetraidrocarbazoli, furo-carbazoli, pirrolocarbazoli, ossazolinilcarbazoli, indolocarbazoli, tionocarbazoli, imidazocarbazoli, tiazolocarbazoli, benzofurano-carbazoli, benzopirano-carbazoli.