Molecular Detection of Human Papilloma Virus in Oral Carcinoma - Al-Malkey, Maysaa Kadhim;Abbas, Ahmed A.H.;Yaseen, Nahi Y.
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The role of human papilloma virus (HPV) as a potential etiological factor in oral carcinoma (OC) has been debated for the last three decades. The pathogenesis of HPV in cervical cancer is well established and the International Agency for Research on Cancer has accepted the role of HPV in several head and neck cancers. However, evidence for a definitive link between HPV and OC remains controversial. Sequence based genotyping (SBG) offers users several advantages including a generic sample preparation method, a uniform bioinformatics workflow strategy to achieve genotyping goals tailored to…mehr

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Produktbeschreibung
The role of human papilloma virus (HPV) as a potential etiological factor in oral carcinoma (OC) has been debated for the last three decades. The pathogenesis of HPV in cervical cancer is well established and the International Agency for Research on Cancer has accepted the role of HPV in several head and neck cancers. However, evidence for a definitive link between HPV and OC remains controversial. Sequence based genotyping (SBG) offers users several advantages including a generic sample preparation method, a uniform bioinformatics workflow strategy to achieve genotyping goals tailored to individual species regardless of the availability of a reference sequence, the most distinguishing feature is the ability to genotype any population structure regardless whether parental data is included, and the ability to co-dominantly score single nucleotide polymorphism (SNP) markers segregating in populations.
Autorenporträt
Dra. Maysaa Kadhim Al-Malkey, Doctora en Microbiología Médica por la Facultad de Medicina de la Universidad de Al-Nahrain. Profesora/investigadora en la Unidad de Investigación Biológica Tropical de la Facultad de Ciencias de la Universidad de Bagdad. Está interesada en los virus causantes del cáncer y en la expresión génica del microARN salival como nueva herramienta de diagnóstico de los carcinomas.