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In the present study an attempt has been made to analyses Demographic and Health Survey data of four selected countries of South Asia namely India, Bangladesh, Nepal and Pakistan at two different survey points. Broadly it is observed that four factors have significant relation with the three indicators of mortality (i.e. on first day, first week and first month). Institutional delivery has a positive effect. Female sex has a negative effect. Longer birth interval (2+) has a negative effect. Working mothers have high mortality of children. Antenatal care (3+) and Tetanus toxide injections (2+) which are essential component of maternal health care do not show any significant relationship with mortality except in India.