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This issue presents topics of importance in current point-of-care testing for laboratory medicine professionals. Topics such as POCT: An overview and look to the future; Fine needle aspiration biopsy:POCT in cytopathology; Drugs of abuse; POCT and disaster response; POCT regulatory affairs; Fecal occult blood testing; Tight Glycemic control;Molecular POCT; Information management and connectivity; Alternate QC and EQC; Managing POCT; and Coagulation and D-dimer.