If you live with relentless exhaustion, post-exertional malaise (PEM), brain fog, or "normal" test results that explain nothing, this book will finally help you understand what's really going on. Millions with ME/CFS, Long Covid, and post-viral fatigue are told their symptoms are a mystery. But emerging research may at last reveal the underlying mechanisms - and offer a path toward meaningful improvement. In this clear, direct, and deeply hopeful guide, ME/CFS patient Patrick Ussher explains the breakthrough model proposed by Professors Klaus Wirth and Carmen Scheibenbogen. Their work brings…mehr
If you live with relentless exhaustion, post-exertional malaise (PEM), brain fog, or "normal" test results that explain nothing, this book will finally help you understand what's really going on. Millions with ME/CFS, Long Covid, and post-viral fatigue are told their symptoms are a mystery. But emerging research may at last reveal the underlying mechanisms - and offer a path toward meaningful improvement. In this clear, direct, and deeply hopeful guide, ME/CFS patient Patrick Ussher explains the breakthrough model proposed by Professors Klaus Wirth and Carmen Scheibenbogen. Their work brings together the major abnormalities seen in ME/CFS - low blood volume, microclots, autonomic dysfunction, mitochondrial impairment, autoimmunity, and more - into one interconnected cycle. It may finally explain why activity triggers PEM, why rest doesn't restore energy, and why so many develop chronic fatigue after a viral illness. This book goes far beyond theory. It offers practical tools, science-based insights, and real-world strategies that patients use to manage symptoms and improve quality of life. Inside, you'll learn about: Breathing techniques to improve oxygenation Ancestral nutrition and gut repair Microclot-oriented treatment approaches Blood-washing procedures (HELP Apheresis & Immunoadsorption) The Perrin Technique The strengths and limits of neuroplasticity ("brain retraining") Pacing, PEM management, and mitochondrial support The promising potential "Mitodicure" medication - the first drug candidate in development specifically for ME/CFS Patrick also shares his own ME/CFS journey with honesty and clarity: what has helped him, what has not, and how he learned to navigate a misunderstood illness with both realism and hope. If you live with: ME/CFS Long Covid post-viral fatigue dysautonomia / POTS unexplained fatigue with normal blood tests ...this book will give you a clear framework for understanding your symptoms and practical strategies that may help you feel better. Straightforward. Evidence-based. Patient-centred. A guide for anyone seeking answers to this - up until now - most 'mysterious' of illnesses. Includes a foreword by Prof. Klaus Wirth, co-developer of the Mitodicure therapy.
Patrick Ussher is a writer, composer, and health communicator who has lived with ME/CFS for seven years. He runs the YouTube channel 'Understanding ME/CFS', where he explores the science of ME/CFS and Long Covid in accessible language and shares personal insights into treatment strategies he has tried. He is the author of the medical hypothesis 'The Myth of Primary Polydipsia', which argues against the concept of 'psychogenic water drinking' and suggests a biomedical basis for thirst in ME/CFS and related illnesses.Patrick regularly gives talks to patient organizations such as The Irish ME Trust and has contributed essays to the ME/CFS blog Health Rising on a range of topics.Outside of health advocacy, Patrick is the author of 'Stoicism and Western Buddhism: A Reflection on Two Philosophical Ways of Life', and the editor of the books 'Stoicism Today: Selected Writings' (Volumes One and Two). In 2018, he worked with Columba Press to republish his late mother's book on coping with breast cancer, 'Following the Pink Ribbon Path'.He holds a BA and MA in Classics from the University of Exeter and is also a composer of contemporary classical music, with tracks available on Spotify and the Artlist catalogue. Originally from Ireland, Patrick has lived in both Ireland and France during his illness.
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