Abdelhafid Mimouni

XAS: Powerful spectroscopy to study cobalamins

• Broschiertes Buch

Produktbeschreibung

My book presents the applications of X-ray absorption spectroscopy (XAS) to the study of cobalamines, a family of organometallic molecules that play an essential role in the metabolism of all living things. I carried out several experiments on synthetic or biological samples, using different variants of XAS, such as XANES or EXAFS. I also used theoretical and numerical tools to interpret my data and compare them with those in the literature.In my book, I invite you to discover :- The base-off/base-on reaction of cobalamines, which modifies the geometry and stability of cobalamines.- The interaction between haptocorrin and cobalamins, which involves a modification of cobalt coordination and protection against oxidation.- The photolysis reaction of alkylcobalamines, leading to the disruption of the cobalt-carbon bond and the formation of a free radical.- Synthesis and characterization of cobaloximes, "model compounds of vitamin B12".- The interaction between glutathione and cobalamins, leading to the formation of glutathione-cobalamin complexes.

Produktdetails

• Verlag: Our Knowledge Publishing
• Seitenzahl: 68
• Erscheinungstermin: 7. November 2023
• Englisch
• Abmessung: 220mm x 150mm x 5mm
• Gewicht: 119g
• ISBN-13: 9786206648833
• ISBN-10: 6206648834
• Artikelnr.: 69358058

Autorenporträt

Investigador independente especializado em química bioinorgânica, o Dr. Mimouni é um perito em XAS. Obteve o seu doutoramento em Química pela Universidade de Paris XII em 1997, depois de ter concluído um Diplôme d'Études Approfondies en Systèmes Bioinorganiques, uma Maîtrise e uma Licence en Chimie, na Universidade de Paris XI em 1993/92/91,