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"The "evolutionary stem cell paradigm?of Z. Ivanovic and M. Vlaski provides the key for understanding and predicting stem cell behavior in vivo and ex vivo, which is of paramount importance for the cell engineering and anti-cancer strategies. The concept of anaerobiosis and stemness presented in this unique book implies the epigenetic missing link in stem cells behavior. The evolutionary paradigm described, although partly hypothetical, is important for understanding developmental biology." --Professor Pavle Milenkovic, MD, PhD, President of the Academy of Medical Sciences, Serbian Medical Society