Jan Jezek, Jan Hlavácek, Jaroslav Sebestík

Biomedical Applications of Acridines (eBook, PDF)

Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases

• Format: PDF

Produktbeschreibung

Describes modern and conventional syntheses of acridine scaffolds

Presents structural aspects of interactions with proteins which provide useful tips for designing enzyme inhibitors involved in the treatment of neurodegenerative diseases

Discusses structural aspects of interactions with nucleic acids, which helps readers to design a specific binder for the targeting of quadruplexes involved in cancer

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Produktdetails

• Verlag: Springer International Publishing
• Seitenzahl: 237
• Erscheinungstermin: 15. August 2017
• Englisch
• ISBN-13: 9783319639536
• Artikelnr.: 53059807

Autorenporträt

 

Inhaltsangabe

Preliminary ToC 1 Introduction.- 2 Nomenclature.- 3. Syntheses.- 4. Interactions of acridines with nucleic acids.- 5. Intercations with proteins.- 6. Applications for treament of neurodegenerative diseases.- 7. Some applications of selective toxicities of acridines.- 8. Acridine on dendrimeric carriers.- 9 Acridines used for staining.- 10 Miscellaneous.- 11 Conclusions and outlook.