Handbook of Proteases in Cancer (eBook, PDF)

Therapeutic Aspects
Redaktion: Chakraborti, Sajal

• Format: PDF

Produktbeschreibung

This handbook provides comprehensive coverage of the application of proteases in cancer therapy. Proteases make up to two percent of the human genome and play a critical role in the tumor microenvironment. The book delves into the applications of natural, synthetic, and non-coding RNAs in cancer therapy. It highlights how effective targeting of relevant proteases can help in cancer diagnosis and treatment. It covers the systems biology and bioinformatics approach in cancer drug development. The book is meant for researchers and professionals in cancer research, biochemistry, and physiology.

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 458
• Erscheinungstermin: 17. Dezember 2024
• Englisch
• ISBN-13: 9781040166543
• Artikelnr.: 72287864

Autorenporträt

Dr. Sajal Chakraborti is associated with the Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India. He conducted postdoctoral research at The Johns Hopkins University School of Medicine, New York Medical College, The University of Utah, and the University of Florida. He has over 35 years of teaching and independent research experience in Biochemistry and Cell Biology. He has published more than 140 original research papers, 25 review articles, and edited 17 books.

Inhaltsangabe

I. General Aspects 1.1. Influence of Serine Proteases on Bone Morphogenetic Proteins: Insights for Advancing Treatment Paradigms in Breast Cancer Anmol Kapoor
Chandi C. Mandal 1.2. Proteases in Cancer Theranostics Deepmala Karmakar
Sanghamitra Sengupta 1.3. Structural aspects of proteases in cancer therapeutics: A perspective Anirban Nandy
Sima Biswas
Angshuman Bagchi II. Proteases in Cancer Therapy 2.1 Ubiquitin specific proteases: The role and potential in cancer immunotherapy Bee Ling Tan1
Ayman El-Meghawry El-Kenawy2
3
Yin Sim Tor4 2.2. Proteasome
the recycle bin of the cancer cell Amy Dunne Miller1
Vasudha Tandon1
Nilabja Sikdar2
Sourav Banerjee1 2.3. The role of caspase 3 in post chemotherapy breast and colorectal cancer relapse and metastasis. Andreja Leskovac
Sandra Petrovic 2.4. Role of Serine Proteases in Gastric Cancer: Inhibition and Cure Reena Kumari1
2
Kshetrimayum Birla Singh2
Amit Kumar Rai1
Sivakumar Vijayaraghavalu2* 2.5. Serine protease inhibitors in breast cancer therapy Abinaya Elango
Arunkumar Radhakrishnan* 2.6. Serine proteases in cancer: Mechanisms and treatment options Madhu Tanya Singh; Ammu V. V. V. Ravi Kiran; Garikapati Kusuma Kumari; Praveen T. Krishnamurthy* 2.7. Survivin
a moonlighting caspase inhibitor and potential oncotherapeutic target Abdul Basit Baba1
Rajakishore Mishra2
Siddavaram Nagini3 2.8. Ubiquitin-specific proteases for the treatment of breast cancer Suchetana Pal1
Subhasish Sarkar2
Rajlakshmi Laha2
Somasri Dam 2.9. Microbial secretory proteases: a new insight in the field of cancer therapies Nanda Singh
Rima Tapader
Amit Pal 2.10. The emerging role of the ¿-secretase inhibitors in cancer management Anuj Kumar Borah1
Chongtham Sovachandra Singh1
Babiangshisha Kharbuli1
Anupam Chatterjee2
Subhendu Chakrabarty3
Amlan Das1 2.11. Cathepsins in cancer therapy and precision medicine Namrata Singh1*
Aqsa Khan2
Asma Mohin Rojewale1
Shinjinee Sengupta2 2.12. The Emerging Role of Calpain 2 Protease as a Therapeutic Target in Breast Cancer Praveen Kumar Chandra Sekar1
Jayakumar Subramaniyan2
Ramakrishnan Veerabathiran1* III. Epigenetic Tools and Stem Cell Therapy 3.1. Calpains
miRNA and cancer: an overview Sajal Chakraborti1*
Mahasweta Ghosh1
Rajabrata Bhuyan2
Dibyapriya Roy Chowdhury1
Tapati Chakraborti1 3.2. The roles of ubiquitin-specific proteases (USPs) in cancer stem cell maintenance. Kuan Ping Anga2
Won Fen Wonga3
Chung Yeng Looi 3.3. Modulatory Effects of Stem Cell Therapy on Cysteine Proteases and Matrix Metaloproteases in Breast Cancer Nour Y. S. Yassin
Noha A. Ahmed
Manal N. Abdel Azeem
Osama M. Ahmed 3.4. Application of metalloproteases in cancer stem cell therapy Uju Dorathy Iliemene1*
Paul T. Olonishuwa1
and Mubarak Labaran Liman2 3.5. Regulatory Mechanisms and Clinical Potential of Epigenetic Targeting in Glioma Yetirajam Rajesh
Suvendu Nandi
Priya Ghosh
Mahitosh Mandal* 3.6. Associations of proteases and long non-coding RNAs in cancer Gaurav Kumar Bhagat1
Dipanjan Guha2
Angshuman Bagchi 3.7. Stem cell-mediated interventions in cancers caused by proteases Farheen Showkata2
Sabra Parveena2
Neetu Badesraa2
Mohmmad Saleem Dar1
2
Md Mehedi Hossaina2
Mir Owais Ayaz1
2
Mohd Jamal Dar1
2 3.8. Stem cell therapy in bone marrow cancer Arjun K R
Girish Kanavi K
Sudipta Choudhury
Mythreyi R
Kanthesh M Basalingappa IV. Nanotechnology Based Therapies 4.1. Protease-targeting nanoparticles for cancer therapy and imaging Sandra Petrovic*
Andreja Leskovac 4.2. Nanomedicine role in proteolytic landscape of breast cancer Sobia Noreen1
Mehwish Ishtiaq1
Sara Hasan1
2
Shazia Akram Ghumman3
Samina Aslam4 4.3. Proteasome Inhibitors and Nano-Delivery Systems for Therapy of Glioblastoma Multiforme Mekala Janaki Ramaiah1
Sahiti Chamarthy1
Janumala Mary Edna1
Katari Sukeerthi2
Nallapaty Srilakshmi2
Prasanna Srinivasan Ramalingam3
Sivakumar Armugam3 4.4. Emerging proteases for molecular imaging and therapy in cancer Presenjit1
2
Shubhra Chaturvedi1
Vishaka Chaudhary1
3
V.P. Singh4
Kaman Singh2
A.K. Mishra1* 4.5. Novel nano technologies associated with Car-T cell therapy in breast cancer Avipsa Hazra1
Ragini Khanna2
Parthiban R3
Gopenath TS4
Kanthesh BM1* V. Bioinformatics and System Biology 5.1. System biology approach of protease Cathepsin K in glioblastoma multiforme Prasanna Srinivasan Ramalingam1
Sivakumar Arumugam1
Purushothaman Balakrishnan2
Janaki Ramaiah Mekala 5.2. Omics technologies for matrix metalloproteinases: MMPs as cancer biomarkers Sherlin Rosita Arockiaraj1
Jay Shree Mathivanan1
Shivani Jambulingam1
Karnati Balaji2
Mahima Bhardwaj2
Pushparaj Annadurai3
Thomas Jebastin1
Abhinav Parashar4
Daniel A. Gideon5* 5.3. Designing Novel Serine Protease Inhibitors against Potential Biomarkers specific to Lung Adenocarcinoma through Systems Biology and Structural Bioinformatics Approaches Anamika Mishra1
Aniket Naha2*
Soundharya H1
Soumitra Nath3*
Nibu Varghese4
Soumya R S5 5.4. System biology and bioinformatics approaches in HTLV-1 protease targeting adult T-cell leukemia disease Chandrabose Selvaraj1
Sanjeev Kumar Singh2
Devadasan Velmurugan 5.5. Protease profiling in lung cancer using bioinformatics tools Protease Profiling in Lung Cancer using Bioinformatics Tools Gowrav Baradwaj
Avipsa Hazra
Dhanu AS and Kanthesh M Basalingappa