Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells (eBook, ePUB)

Redaktion: Lo, Kenneth Kam-Wing

• Format: ePub

Produktbeschreibung

Inorganic and Organometallic Transition Metal Complexes with Biological Molecules and Living Cells provides a complete overview of this important research area that is perfect for both newcomers and expert researchers in the field. Through concise chapters written and edited by esteemed experts, this book brings together a comprehensive treatment of the area previously only available through scattered, lengthy review articles in the literature. Advanced topics of research are covered, with particular focus on recent advances in the biological applications of transition metal complexes, including inorganic medicine, enzyme inhibitors, antiparasital agents, and biological imaging reagents. - Geared toward researchers and students who seek an introductory overview of the field, as well as researchers working in advanced areas - Focuses on the interactions of inorganic and organometallic transition metal complexes with biological molecules and live cells - Foscuses on the fundamentals and their potential therapeutic and diagnostic applications - Covers recent biological applications of transition metal complexes, such as anticancer drugs, enzyme inhibitors, bioconjugation agents, chemical biology tools, and bioimaging reagents

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 406
• Erscheinungstermin: 30. Dezember 2016
• Englisch
• ISBN-13: 9780128038871
• Artikelnr.: 47357737

Autorenporträt

Kenneth Lo is a Chair Professor of Inorganic Chemistry at City University of Hong Kong, specializing in luminescent inorganic and organometallic transition metal complexes for biomolecular and cellular applications. His research includes developing intracellular sensors, photoactive labels, bioimaging reagents, and photocytotoxic agents. He has received prestigious awards, including the APA Prize for Young Scientist (2005), the Distinguished Lectureship Award from the Chemical Society of Japan (2011), the Hans Freeman Lectureship from the University of Sydney (2024), and the Elsevier Lectureship Award from the Japanese Photochemistry Association (2025). He was awarded a Croucher Senior Research Fellowship (2015) and became a Fellow of the Royal Society of Chemistry (2018). Professor Lo chaired the Gordon Research Conference on Metals in Medicine (2018) and the 23rd International Symposium on Photochemistry and Photophysics of Coordination Compounds (2019). Since 2020, he has serve

d as an Associate Editor for the ACS journal Inorganic Chemistry.

Inhaltsangabe

1. Luminescent Zinc Complexes as Bioprobes for Imaging Molecular Events in Live Cells
2. Cellular Uptake and Sensing Capability of Transition Metal Peptide Conjugates
3. Luminescent Rhenium(I) and Iridium(III) Complexes for Intracellular Labeling, Sensing, and Photodynamic Therapy Applications
4. Organoruthenium(II)-Arene Complexes: Structural Building Blocks for Anticancer Drug Discovery
5. Medicinal Chemistry of Metal N-Heterocyclic Carbene (NHC) Complexes
6. Metal Complexes as Delivery Systems for CO, NO, and H₂S to Explore the Signaling Network of Small-Molecule Messengers
7. Antimicrobial Metallodrugs
8. Carbon Nanotubes and Related Nanohybrids Incorporating Inorganic Transition Metal Compounds and Radioactive Species as Synthetic Scaffolds for Nanomedicine Design
9. Immobilized Metal Affinity Chromatography (IMAC) for Metalloproteomics and Phosphoproteomics
10. The Analysis of Therapeutic Metal Complexes and Their Biomolecular Interactions