Insulin-like Growth Factors and Cancer (eBook, PDF)

From Basic Biology to Therapeutics
Redaktion: Leroith, Derek

• Format: PDF

Produktbeschreibung

The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 284
• Erscheinungstermin: 18. September 2011
• Englisch
• ISBN-13: 9781461405986
• Artikelnr.: 37349695

Inhaltsangabe

Preface.- Epidemiology of IGF-1 and Cancer.- Aging and Cancer: The IGF-I Connection.- Obesity, Type 2 Diabetes and Cancer.- IGF System and Breast Cancer.- The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression.- Mouse Models of IGF-1 Deficiency.- Insulin-like Growth Factor Signaling in Pediatric Sarcomas.- Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer.- Mouse Models of IGF-1R and Cancer.- Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy.- Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer.- Calories and Cancer: The Role of Insulin-like Growth Factor.- Cancer Cell Metabolism.- Overlaps between the Insulin and IGF-1R and Cancer.- Index