Sie sind bereits eingeloggt. Klicken Sie auf 2. tolino select Abo, um fortzufahren.
Bitte loggen Sie sich zunächst in Ihr Kundenkonto ein oder registrieren Sie sich bei bücher.de, um das eBook-Abo tolino select nutzen zu können.
The book offers a thorough exploration of revolutionary nano-biosensor technologies that enables rapid, accurate detection of infectious diseases, critical for effective disease management in today's world. Nano-Biosensor Technologies for Diagnosis of Infectious Diseases delves into the cutting-edge developments in nano-biosensor technology, a transformative innovation for the field of medical diagnostics. Nano-biosensors integrate nanomaterials like nanoparticles, nanowires, and nanotubes with biological recognition elements such as antibodies, nucleic acids, or enzymes to create highly…mehr
The book offers a thorough exploration of revolutionary nano-biosensor technologies that enables rapid, accurate detection of infectious diseases, critical for effective disease management in today's world.
Nano-Biosensor Technologies for Diagnosis of Infectious Diseases delves into the cutting-edge developments in nano-biosensor technology, a transformative innovation for the field of medical diagnostics. Nano-biosensors integrate nanomaterials like nanoparticles, nanowires, and nanotubes with biological recognition elements such as antibodies, nucleic acids, or enzymes to create highly sensitive and specific detection systems. These sensors exploit unique properties of nanomaterials to detect minute quantities of pathogens or biomarkers with remarkable accuracy, enabling early diagnosis and monitoring of infectious diseases. The integration of electrochemical, optical, and piezoelectric detection mechanisms further enhances the versatility and efficiency of these nano-biosensors, allowing for rapid, real-time analysis that is crucial for effective disease management.
In the context of infectious diseases, nano-biosensors become particularly significant, as they can facilitate point-of-care testing (POCT), offering rapid and portable diagnostic solutions. This capability is invaluable in resource-limited settings and during outbreaks where traditional laboratory infrastructure may be lacking. The COVID-19 pandemic underscores the importance of swift and accurate diagnostic tools, spurring accelerated innovation and commercialization efforts in this domain. Nano-biosensors are now being developed and deployed to detect a wide range of pathogens with high sensitivity, providing a powerful tool in the global fight against infectious diseases. Nano-Biosensor Technologies for Diagnosis of Infectious Diseases provides a comprehensive overview of these technological advancements, exploring their applications, challenges, and future directions in the diagnosis and management of infectious diseases.
Audience
Biomedical engineers, material chemists, researchers, students, policymakers, and healthcare professionals interested in integrating nanomaterials in infectious disease care
Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in D ausgeliefert werden.
Die Herstellerinformationen sind derzeit nicht verfügbar.
Autorenporträt
Suvardhan Kanchi, Ph.D., is an associate professor of the Department of Chemistry, Sambhram Institute of Technology, Bengaluru, India. He is also a senior researcher in novel method development and validation. He has a Ph.D. in analytical chemistry. His expertise is in field-flow fractionation techniques. He has conducted studies in the scientific literature, gathered and analyzed data, and improved decision-making processes. In his research, Kanchi has developed new nanomaterials and devices that detect temperature. Ayyappa Bathinapatla, M.D, Ph.D., is an assistant professor in the Department of Chemistry, CMR Institute of Technology, Bengaluru, India. He obtained a Ph.D. from Durban University of Technology, South Africa, in 2012. Bathinapatia is fond of researching the determination of organic and inorganic compounds using capillary electrophoresis. In addition, he also researches applications of nanomaterials in the field of energy production. He has 13 research publications in various international journals and filed patents. Anitha Varghese, Ph.D., is a professor and head of the Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India. She received a Ph.D. in chemistry from Mangalore University, Karnataka, India in 2007. She has published 96 academic papers and earned six patents. Varghese has won several awards, such as the Woman of the Year award in 2020 from CHRIST (Deemed to be University), Bangalore, India. Phumlane Mdluli, Ph.D., is the head of the health platform in the advanced material division at the Nanotechnology Innovation Centre, Mintek, Randburg, South Africa. He obtained a Ph.D. from the University of Zululand, South Africa, in 2009. He has published 73 academic papers. Mdluli was awarded the Mintek Apex Award for developing rapid diagnostic lateral flow assays and won the Best Researcher Award in the Faculty and Department of Chemistry at the Durban University of Technology.
Inhaltsangabe
Preface xv 1 Biosensor Technology: Basic Principles, Fundamentals, and History 1 Mariyam Thomas, Mathew George, Derry Holaday M. G. and P. J. Jandas 1.1 Introduction 2 References 20 2 Design and Synthesis of Novel Nanomaterials Emphasizing Infectious Diseases 23 Prasann Kumar and Joginder Singh 2.1 Introduction 24 2.2 Antifungal Therapy 26 2.3 Cutting-Edge Advances in Tailoring the Size, Shape, and Functionality of Nanoparticles and Nanostructures 28 2.4 Gold Silver Nanoparticle to Combat Multi-Drug Resistant Pathogen 30 2.5 Mechanism of Gold Silver Nanoparticle to Combat Multi-Drug Resistant Pathogen 31 2.6 MXenes and Borophene Nanomaterials: Highly Efficient Sensor Activity and Energy Storage Properties 34 2.7 Immunomodulatory Nanosystems 39 2.8 Lateral Flow Assays (LFAs) 40 2.9 Metal-Organic Framework (MOF) 43 2.10 Microfluidic Devices: For Detecting Disease-Specific Proteins 45 2.11 Comprehensive Overview of Nanomaterials in the Context of Cutaneous Leishmaniasis 47 2.12 Graphene Oxide (GO): A Two-Dimensional (2D) Nanomaterial 55 Conclusion 65 Future Prospect 66 Acknowledgement 67 Authors' Contributions 68 References 68 3 Role of Nanomaterials in the Development of Nanobiosensors for Infectious Diseases 75 Ayyappa Bathinapatla, Ravikumar Mulpuri, Aseena Azeez and Suvardhan Kanchi 3.1 Introduction 76 3.2 Designing Biosensor for SARS-CoV-2 83 3.3 Conclusions and Future Perspectives 112 References 113 4 Nanobiosensors: Versatile Tool for Diagnosis of Infectious Diseases 121 Prasann Kumar and Joginder Singh 4.1 Introduction 122 4.2 Nanobiosensors as Promising Devices for the Diagnosis of Coronavirus Family Members 123 4.3 Nanobiosensors for Plant Analysis 129 4.4 Three-Way Junctions Skeleton of Biosensor 135 4.5 The SpACE-CCM: Biosensor for Detection of SARS-CoV-2 Spike-ACE2 Interaction 142 4.6 Wearable Biosensor Nano and Microsystems Have Emerged as Innovative Solutions for Medical Diagnostics 146 4.7 Biosensors are Analytical Devices 153 4.8 Conclusion 159 Acknowledgement 160 Authors' Contributions 160 References 160 5 Trends in the Development of Immunosensors for the Diagnosis of Infectious Diseases 173 Stephen Rathinaraj Benjamin, Eli José Miranda Ribeiro Júnior, Sam Phinehas Gnana Sekar, Rosa Fireman Dutra and Geanne Matos de Andrade 5.1 Introduction 174 5.2 Immunosensors 178 5.3 Optical Immunosensor 180 5.4 Nanomaterials Immunosensor 183 5.5 Paper-Based Immunosensors 185 5.6 Viral Infectious Diseases 185 5.7 Future Perspectives and Conclusion 190 Acknowledgements 191 References 191 6 Electrochemical Nanobiosensors Approaches for Rapid Diagnosis of Infectious Diseases 197 Tahmina Foyez and Abu Bin Imran 6.1 Introduction 198 6.2 Conventional Methods for the Determination of Infectious Pathogens 199 6.3 Building Blocks of Biosensor 202 6.4 Electrochemical-Based Biosensors 206 6.5 Impact of Nanomaterials on Biosensor Performance 209 6.6 Noble Metal Nanomaterials 210 6.7 Metal Oxide Nanomaterials 214 6.8 Carbon Nanomaterials 216 6.9 Polymer Nanomaterials 218 6.10 Bionanomaterials 220 6.11 Conclusions and Future Perspectives 222 Acknowledgement 223 References 223 7 Enzymatic Nanobiosensor Strategies to Contain the Spread of Infectious Diseases 231 Soumendu Patra, Harshita Shand, Swarnab Dutta, Rittick Mondal and Suvankar Ghorai 7.1 Introduction 232 7.2 Components of Enzymatic Biosensor 233 7.3 Enzymatic Nanobiosensors for Pathogen Detection 234 7.4 Nanozymes 235 7.5 Future Aspects 237 References 238 8 Development of Optical Nanosensors for the Detection of Infectious Diseases 241 Ndivhuwo Shumbula, Nosipho Moloto, Phumlane Mdluli and Mbuso Mlambo 8.1 Introduction 242 8.2 Overview of Biosensor 243 8.3 Introduction to Optical Nanosensors 246 8.4 Remarks 262 References 265 9 Aptasensors: Selective and Powerful Tools for Infectious Diseases Diagnosis 279 Seele, P. P., Van der Walt, H., Sibuyi, N.R.S. and Maserumule, M.C. 9.1 Introduction 280 9.2 Aptamers as Selective and Powerful Tools for Diagnostics 281 9.3 Synthesis of Aptamers 288 9.4 Application of Aptasensors in PoC Diagnostics 293 9.5 Aptasensors Impact on Infectious Disease Diagnosis 296 9.6 Drawbacks and Potential Future Work 302 9.7 Conclusions 303 References 303 10 Nanobiosensors: A Platform for the Diagnosis of Microbial Pathogens 315 Ranjita Misra and Naomi Sanjana Sharath 10.1 Introduction 316 10.2 Microbial Pathogens 317 10.3 Diseases Caused by Pathogens 319 10.4 Importance of Pathogen Detection or Disease Diagnosis 320 10.5 Biosensors 322 10.6 Nanobiosensors as Diagnostic Platform 323 10.7 Stabilization of Biomolecules with Nanoparticles 325 10.8 Types of Nanoparticles Used in Biosensor Development 328 10.9 Challenges and Future Prospects 332 Conclusion 333 References 334 11 Micro/Nanofluidics-Integrated Biosensors for Respiratory Viral Diseases Diagnosis 341 Aiswarya Chandrasekaran and G.H.R. Eranga Karunaratne 11.1 Introduction 342 11.2 Common Respiratory Viruses and Their Detection Components 343 11.3 Biosensors 345 11.4 Fluidic Technology 347 11.5 Applications of Micro/Nanofluidic-Based Biosensors in Respiratory Virus Detection 352 11.6 Advantages of Micro/Nanofluidic Diagnosis Tools Over the Other Diagnostic Methods 356 11.7 Conclusion and Future Perspectives 356 References 357 12 Nanobiosensor System: A Robust Analytical Tool for Pandemics 365 Mohammad Harun-Ur-Rashid, Israt Jahan and Abu Bin Imran 12.1 Introduction 366 12.2 Nanobiosensors for Global Pandemics 369 12.3 Nanobiosensors for COVID-19 375 12.4 Nanobiosensors for Influenza 378 12.5 Nanobiosensors for MERS 381 12.6 Nanobiosensors for HIV/AIDS 383 12.7 Nanobiosensors for Other Human Viruses 385 12.8 Selection and Optimization of Nanomaterials for Nanobiosensors 387 12.9 Current Challenges and Prospective Solutions 391 12.10 Conclusion 392 References 393 13 Biosensing Technologies to Improve Neurological Disease Management 401 Poojith Nuthalapati, Arjun Singh, Brinda Niravkumar Desai, Preeti Reddy Yendapalli, Reethika Gongireddy, Karan Singh, Bhaswanth Bollu and Dheeraj K. Pinninty 13.1 Introduction 402 13.2 Trends, Challenges, and the Disease Burden 404 13.3 CNS Diseases 404 13.4 Utility of Neurobiosensors 405 13.5 The Technology Behind Biosensor Development 406 13.6 Clinical Applications 413 13.7 Conclusion 415 References 416 14 Nanotechnology-Based Strategies for Improvement of Disease Diagnostic Systems for Future Outbreaks 423 Busiswa Dyan, Tintswalo N. Mgwenya, Kamogelo S. Setlolamathe, Phumlane S. Mdluli and Nicole R.S. Sibuyi 14.1 Introduction 424 14.2 Infectious Disease Outbreaks 424 14.3 Pandemic-Potential Priority Diseases for Future Outbreaks 432 14.4 Combating Infectious Diseases Through Diagnostics 434 14.5 Nanotechnology in Diagnostics 438 14.6 Conclusion 440 References 441 15 Biocompatibility and Toxicity of Nanomaterials in the Designing of Tools for the Diagnosis of Infectious Diseases 449 Manju Manuel 15.1 Introduction 450 15.2 An Overview of Nanomaterials in Infectious Disease Diagnosis 451 15.3 Biocompatibility Assessment 453 15.4 Mechanism of Nanoparticles in the Infectious Disease Diagnosis 455 15.5 In Vitro and In Vivo Evaluation Methods of Biocompatibility Analysis 458 15.6 Toxicity of Nanomaterials 458 15.7 The Environmental and Health Hazards Caused by Nanoparticles 461 15.8 The Tools Developed for the Diagnosis of Infectious Diseases 462 15.9 Conclusion 464 References 464 16 Strengthening the Health System of the Communities in the Battle Against Infectious Diseases 469 Dinoy Mathew, Anu P. Mathew, Bobby Simon and Ancy Joseph 16.1 Introduction 470 16.2 Primary Healthcare 471 16.3 Impact of COVID-19 on Infectious Diseases and Health Systems 476 16.4 Conclusion 480 References 480 Index 485
Preface xv 1 Biosensor Technology: Basic Principles, Fundamentals, and History 1 Mariyam Thomas, Mathew George, Derry Holaday M. G. and P. J. Jandas 1.1 Introduction 2 References 20 2 Design and Synthesis of Novel Nanomaterials Emphasizing Infectious Diseases 23 Prasann Kumar and Joginder Singh 2.1 Introduction 24 2.2 Antifungal Therapy 26 2.3 Cutting-Edge Advances in Tailoring the Size, Shape, and Functionality of Nanoparticles and Nanostructures 28 2.4 Gold Silver Nanoparticle to Combat Multi-Drug Resistant Pathogen 30 2.5 Mechanism of Gold Silver Nanoparticle to Combat Multi-Drug Resistant Pathogen 31 2.6 MXenes and Borophene Nanomaterials: Highly Efficient Sensor Activity and Energy Storage Properties 34 2.7 Immunomodulatory Nanosystems 39 2.8 Lateral Flow Assays (LFAs) 40 2.9 Metal-Organic Framework (MOF) 43 2.10 Microfluidic Devices: For Detecting Disease-Specific Proteins 45 2.11 Comprehensive Overview of Nanomaterials in the Context of Cutaneous Leishmaniasis 47 2.12 Graphene Oxide (GO): A Two-Dimensional (2D) Nanomaterial 55 Conclusion 65 Future Prospect 66 Acknowledgement 67 Authors' Contributions 68 References 68 3 Role of Nanomaterials in the Development of Nanobiosensors for Infectious Diseases 75 Ayyappa Bathinapatla, Ravikumar Mulpuri, Aseena Azeez and Suvardhan Kanchi 3.1 Introduction 76 3.2 Designing Biosensor for SARS-CoV-2 83 3.3 Conclusions and Future Perspectives 112 References 113 4 Nanobiosensors: Versatile Tool for Diagnosis of Infectious Diseases 121 Prasann Kumar and Joginder Singh 4.1 Introduction 122 4.2 Nanobiosensors as Promising Devices for the Diagnosis of Coronavirus Family Members 123 4.3 Nanobiosensors for Plant Analysis 129 4.4 Three-Way Junctions Skeleton of Biosensor 135 4.5 The SpACE-CCM: Biosensor for Detection of SARS-CoV-2 Spike-ACE2 Interaction 142 4.6 Wearable Biosensor Nano and Microsystems Have Emerged as Innovative Solutions for Medical Diagnostics 146 4.7 Biosensors are Analytical Devices 153 4.8 Conclusion 159 Acknowledgement 160 Authors' Contributions 160 References 160 5 Trends in the Development of Immunosensors for the Diagnosis of Infectious Diseases 173 Stephen Rathinaraj Benjamin, Eli José Miranda Ribeiro Júnior, Sam Phinehas Gnana Sekar, Rosa Fireman Dutra and Geanne Matos de Andrade 5.1 Introduction 174 5.2 Immunosensors 178 5.3 Optical Immunosensor 180 5.4 Nanomaterials Immunosensor 183 5.5 Paper-Based Immunosensors 185 5.6 Viral Infectious Diseases 185 5.7 Future Perspectives and Conclusion 190 Acknowledgements 191 References 191 6 Electrochemical Nanobiosensors Approaches for Rapid Diagnosis of Infectious Diseases 197 Tahmina Foyez and Abu Bin Imran 6.1 Introduction 198 6.2 Conventional Methods for the Determination of Infectious Pathogens 199 6.3 Building Blocks of Biosensor 202 6.4 Electrochemical-Based Biosensors 206 6.5 Impact of Nanomaterials on Biosensor Performance 209 6.6 Noble Metal Nanomaterials 210 6.7 Metal Oxide Nanomaterials 214 6.8 Carbon Nanomaterials 216 6.9 Polymer Nanomaterials 218 6.10 Bionanomaterials 220 6.11 Conclusions and Future Perspectives 222 Acknowledgement 223 References 223 7 Enzymatic Nanobiosensor Strategies to Contain the Spread of Infectious Diseases 231 Soumendu Patra, Harshita Shand, Swarnab Dutta, Rittick Mondal and Suvankar Ghorai 7.1 Introduction 232 7.2 Components of Enzymatic Biosensor 233 7.3 Enzymatic Nanobiosensors for Pathogen Detection 234 7.4 Nanozymes 235 7.5 Future Aspects 237 References 238 8 Development of Optical Nanosensors for the Detection of Infectious Diseases 241 Ndivhuwo Shumbula, Nosipho Moloto, Phumlane Mdluli and Mbuso Mlambo 8.1 Introduction 242 8.2 Overview of Biosensor 243 8.3 Introduction to Optical Nanosensors 246 8.4 Remarks 262 References 265 9 Aptasensors: Selective and Powerful Tools for Infectious Diseases Diagnosis 279 Seele, P. P., Van der Walt, H., Sibuyi, N.R.S. and Maserumule, M.C. 9.1 Introduction 280 9.2 Aptamers as Selective and Powerful Tools for Diagnostics 281 9.3 Synthesis of Aptamers 288 9.4 Application of Aptasensors in PoC Diagnostics 293 9.5 Aptasensors Impact on Infectious Disease Diagnosis 296 9.6 Drawbacks and Potential Future Work 302 9.7 Conclusions 303 References 303 10 Nanobiosensors: A Platform for the Diagnosis of Microbial Pathogens 315 Ranjita Misra and Naomi Sanjana Sharath 10.1 Introduction 316 10.2 Microbial Pathogens 317 10.3 Diseases Caused by Pathogens 319 10.4 Importance of Pathogen Detection or Disease Diagnosis 320 10.5 Biosensors 322 10.6 Nanobiosensors as Diagnostic Platform 323 10.7 Stabilization of Biomolecules with Nanoparticles 325 10.8 Types of Nanoparticles Used in Biosensor Development 328 10.9 Challenges and Future Prospects 332 Conclusion 333 References 334 11 Micro/Nanofluidics-Integrated Biosensors for Respiratory Viral Diseases Diagnosis 341 Aiswarya Chandrasekaran and G.H.R. Eranga Karunaratne 11.1 Introduction 342 11.2 Common Respiratory Viruses and Their Detection Components 343 11.3 Biosensors 345 11.4 Fluidic Technology 347 11.5 Applications of Micro/Nanofluidic-Based Biosensors in Respiratory Virus Detection 352 11.6 Advantages of Micro/Nanofluidic Diagnosis Tools Over the Other Diagnostic Methods 356 11.7 Conclusion and Future Perspectives 356 References 357 12 Nanobiosensor System: A Robust Analytical Tool for Pandemics 365 Mohammad Harun-Ur-Rashid, Israt Jahan and Abu Bin Imran 12.1 Introduction 366 12.2 Nanobiosensors for Global Pandemics 369 12.3 Nanobiosensors for COVID-19 375 12.4 Nanobiosensors for Influenza 378 12.5 Nanobiosensors for MERS 381 12.6 Nanobiosensors for HIV/AIDS 383 12.7 Nanobiosensors for Other Human Viruses 385 12.8 Selection and Optimization of Nanomaterials for Nanobiosensors 387 12.9 Current Challenges and Prospective Solutions 391 12.10 Conclusion 392 References 393 13 Biosensing Technologies to Improve Neurological Disease Management 401 Poojith Nuthalapati, Arjun Singh, Brinda Niravkumar Desai, Preeti Reddy Yendapalli, Reethika Gongireddy, Karan Singh, Bhaswanth Bollu and Dheeraj K. Pinninty 13.1 Introduction 402 13.2 Trends, Challenges, and the Disease Burden 404 13.3 CNS Diseases 404 13.4 Utility of Neurobiosensors 405 13.5 The Technology Behind Biosensor Development 406 13.6 Clinical Applications 413 13.7 Conclusion 415 References 416 14 Nanotechnology-Based Strategies for Improvement of Disease Diagnostic Systems for Future Outbreaks 423 Busiswa Dyan, Tintswalo N. Mgwenya, Kamogelo S. Setlolamathe, Phumlane S. Mdluli and Nicole R.S. Sibuyi 14.1 Introduction 424 14.2 Infectious Disease Outbreaks 424 14.3 Pandemic-Potential Priority Diseases for Future Outbreaks 432 14.4 Combating Infectious Diseases Through Diagnostics 434 14.5 Nanotechnology in Diagnostics 438 14.6 Conclusion 440 References 441 15 Biocompatibility and Toxicity of Nanomaterials in the Designing of Tools for the Diagnosis of Infectious Diseases 449 Manju Manuel 15.1 Introduction 450 15.2 An Overview of Nanomaterials in Infectious Disease Diagnosis 451 15.3 Biocompatibility Assessment 453 15.4 Mechanism of Nanoparticles in the Infectious Disease Diagnosis 455 15.5 In Vitro and In Vivo Evaluation Methods of Biocompatibility Analysis 458 15.6 Toxicity of Nanomaterials 458 15.7 The Environmental and Health Hazards Caused by Nanoparticles 461 15.8 The Tools Developed for the Diagnosis of Infectious Diseases 462 15.9 Conclusion 464 References 464 16 Strengthening the Health System of the Communities in the Battle Against Infectious Diseases 469 Dinoy Mathew, Anu P. Mathew, Bobby Simon and Ancy Joseph 16.1 Introduction 470 16.2 Primary Healthcare 471 16.3 Impact of COVID-19 on Infectious Diseases and Health Systems 476 16.4 Conclusion 480 References 480 Index 485
Es gelten unsere Allgemeinen Geschäftsbedingungen: www.buecher.de/agb
Impressum
www.buecher.de ist ein Internetauftritt der buecher.de internetstores GmbH
Geschäftsführung: Monica Sawhney | Roland Kölbl | Günter Hilger
Sitz der Gesellschaft: Batheyer Straße 115 - 117, 58099 Hagen
Postanschrift: Bürgermeister-Wegele-Str. 12, 86167 Augsburg
Amtsgericht Hagen HRB 13257
Steuernummer: 321/5800/1497
USt-IdNr: DE450055826
