Peptide Transport and Delivery into the Central Nervous System (eBook, PDF)

Redaktion: Prokai, Laszlo; Prokai-Tatrai, Katalin

• Format: PDF

Produktbeschreibung

Various peptides native to the brain and the spinal cord, as well as various synthetic peptides, peptide analogues and peptidomimetics could be useful in the treatment of diseases of the central nervous system. This book provides an overview of the role and neuropharmaceutical potential of these peptides, and discusses the state of the art and future trends in the use of peptide pharmacotherapy involving the brain.

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Produktdetails

• Verlag: Springer Basel
• Seitenzahl: 245
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783034880497
• Artikelnr.: 53179518

Autorenporträt

Various peptides native to the brain and the spinal cord, as well as various synthetic peptides, peptide analogues and peptidomimetics could be useful in the treatment of diseases of the central nervous system. This book provides an overview of the role and neuropharmaceutical potential of these peptides, and discusses the state of the art and future trends in the use of peptide pharmacotherapy involving the brain.

Inhaltsangabe

Neuropeptides: general characteristics and neuropharmaceutical potential in treating CNS disorders.- Structural and functional aspects of the blood-brain barrier.- Peptide transport across the blood-brain barrier.- Intracranial delivery of proteins and peptides as a therapy for neurodegenerative diseases.- Altering the properties of the blood-brain barrier: disruption and permeabilization.- Modifying peptide properties by prodrug design for enhanced transport into the CNS.- CNS-delivery via conjugation to biological carriers: physiological-based approaches.- Peptide vectors as drug carriers.- Index Vol. 61.