Plasma Membrane Shaping (eBook, ePUB)

Redaktion: Suetsugu, Shiro

• Format: ePub

Produktbeschreibung

Plasma Membrane Shaping summarizes current knowledge on how cells shape their membrane. Organized in four sections, the book opens with a broad overview of the plasma membrane, its composition, usual shapes and substructures, Actin/WASP/arp2/3 structures, BAR domains, and Ankyrin repeat domains, dynamin, and phospholipid signaling. Other sections cover the shaping of the plasma membrane for transport processes, discussions on exosomes, microvesicles, and endosomes, clathrin-coated pits, caveolae, and other endocytic pits, membrane deformation for cell movement, and some of the most current dry and wet lab research techniques to investigate cellular membrane shaping. This is an ideal resource for new researchers coming into this area as well as for graduate students. The methods section will be of interest to both microscopists and computer scientists dedicated to the visualization, data collection, and analysis of plasma membrane shaping experiments. - Covers membrane shaping for both cytosis and cell movement - Includes dry and wet lab research methods of plasma membrane shaping - Describes the molecular machinery involved with protein and lipid balance in the plasma membrane - Presents the coordination of cellular structures involved in cell deformation and motion

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 468
• Erscheinungstermin: 8. September 2022
• Englisch
• ISBN-13: 9780323899192
• Artikelnr.: 65685675

Inhaltsangabe

1. Introduction and overview of the book
Part 1: Building blocks and the shape builders
2. Membrane lipid compositions and the difference between subcellular
structures
3. Wiskott4. BAR domains
5. Ankyrin repeat domains with an amphipathic helix for membrane
deformation
6. Ankyrin repeat domains
7. Dynamin: molecular scissors for membrane fission
8. Phospholipid signaling, lipase
9. Phospholipid signaling: phosphoinositide kinases and phosphatases
10. Plasma membrane shaping by protein phase separation
11. Synthetic mimics of membrane-active proteins and peptides
Part 2: The functions of the plasma membrane substance and derived vesicles
12. The extracellular vesicles
13. Regulation of membrane traffic through recycling endosomes by membrane
phospholipid phosphatidylserine
14. Membrane shaping for clathrin-coated pits and endocytosis
15. Caveolae biogenesis and lipid sorting at the plasma membrane
16. Non-vesicular lipid transport at membrane contact sites between the
endoplasmic reticulum and the plasma membrane
17. Lamellipodia and filopodia
18. Membrane structures, dynamics, and shaping in invadopodia and podosomes
Part 3: Force around the plasma membrane and imaging
19. Membrane tension and mechanobiology of cell migration
20. Brownian ratchet force sensor at the contacting point between F-actin
barbed end and lamellipodium tip plasma membrane
21. Biophysics of cellular membrane shaping on fiber networks
22. Reconstitution of membrane symmetry breaking
Part 4: The microscopy and image analysis for understanding the shaping of
the membrane
23. Imaging three-dimensional dynamics of plasma membrane structures using
ultrathin plane illumination microscopy
24. Deep learning for cell shape analysis
Part 5: The essentiality of the membrane shaping by theory and
reconstitution
25. Physical principles of cellular membrane shapes
26. Modeling cellular shape changes in the presence of curved membrane
proteins and active cytoskeletal forces
27. Molecular dynamics