Marcos Luciano Bruschi

Strategies to Modify the Drug Release from Pharmaceutical Systems (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Since the earliest dosage forms to modern drug delivery systems, came a great development and growth of knowledge with respect to drug delivery. Strategies to Modify the Drug Release from Pharmaceutical Systems will address principles, systems, applications and advances in the field.It will be principally a textbook and a reference source of strategies to modify the drug release. Moreover, the characterization, mathematical and physicochemical models, applications and the systems will be discussed.

• Addresses the principles, systems, applications and advances in the field of drug delivery
• Highlights the mathematical and physicochemical principles related to strategies
• Discusses drug release and its possible modifications

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 208
• Erscheinungstermin: 16. Juni 2015
• Englisch
• ISBN-13: 9780081001127
• Artikelnr.: 43810531

Autorenporträt

Marcos Luciano Bruschi, Ph.D., is Professor of Pharmaceutics andPharmaceutical Technology in the Department of Pharmacy at the State University of Maringá (UEM), Paraná, Brazil. He gained a BSc in Pharmacy (1996 - UEM, Brazil), a MD in Pharmaceutical Sciences (2002 - State University of São Paulo - UNESP - Brazil) and a PhD in Pharmaceutical Sciences (2006 - University of São Paulo - USP - Brazil and School of Pharmacy, Queen's University of Belfast, Northern Ireland, UK). In 2013-2014, he is accomplishing a Post-Doctoral Degree in Pharmaceutics in the School of Pharmacy, Queen's University of Belfast (QUB - Northern Ireland, UK). He is registered with the Brazilian Pharmaceutical Society and, in 1998, took up a lectureship in Pharmaceutics in the School of Pharmacy, UEM, Brazil. In 1999, he was appointed as a senior lectureship and to a personal Chair in Pharmaceutics and Pharmaceutical Technology in 2006. His research concerns the development and characterization of pharmaceutical dosage forms and drug delivery systems, using natural or synthetic sources. Dr. Bruschi's work has involved the development of novel drug delivery systems, with particular emphasis on micro/nanoparticles, semisolids, bio/mucoadhesives, thermoresponsive systems, liquid crystaline phases, and natural products. He is the author of three Brazilian patent requests and over 150 research papers/communications.

Inhaltsangabe

Chapter 1 - General considerations
Pharmaceutics: Safety, quality and efficacy
Conventional and alternative therapeutic regimens
Chapter 2 - Modification of drug release
Objectives
Advantages
Disadvantages
History
Chapter 3 - Classification of therapeutic systems for drug delivery
Passives, pre-programmed
Actives, programmed and controlled externally
Actives, self-programmable
Chapter 4 - Main mechanisms to control the drug release
Diffusion
Swelling
Erosion
Osmosis
Others
Chapter 5 - Mathematical and physicochemical models of drug release
Chapter 6 - Drug delivery systems: Principles, local of administration, materials, characterization, applications, advances and the use of natural products
Matrix Tablets
Suspensions
Osmotic Pumps
Micro/nanoparticles
Micro/nanoemulsioned systems
Liposomes and niosomes
Floating Systems
Systems with cyclodextrins
Transdermal systems
Bio/mucoadhesive Systems
Liquid crystalline systems
Implant
Biocompatible carriers
Other systems