Toxicology of the Liver (eBook, PDF)

Redaktion: Plaa, Gabriel L; Hewitt, Wr

• Format: PDF

Produktbeschreibung

This second edition looks at the physiologic, biochemical, and morphologic characteristics of hepatotoxicity and includes an analysis of techniques in molecular biology and immunochemistry, among others contributing to the growth in understanding of the toxic events involved. It focuses on clinical characterization of chemical hepatotoxicity, micro

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Produktdetails

• Verlag: Taylor & Francis eBooks
• Seitenzahl: 431
• Erscheinungstermin: 27. Februar 1998
• Englisch
• ISBN-13: 9781439810446
• Artikelnr.: 58255130

Autorenporträt

Gabriel L Plaa, WR Hewitt

Inhaltsangabe

1. Drug-induced Hepatic Disease Hyman Zimmerman 2. Morphological Characteristics of Chemical-induced Hepatotoxicity in Laboratory Rodents Paul Newberne and James Newberne 3. Chemical Induced Hepatocarcinogenesis James Klaunig and Kyle Kolaja 4. An Overview of Peroxisome Proliferation Jeffrey Lawrence and Patrick Eacho 5. Acetaminophen-induced Hepatotoxicity Steven Cohen
Debie Hoivik and Edward Khairallah 6. Evaluation of Chemical-induced Oxidative Stress as a Mechanism of Hepatocyte Death Donald Reed 7. Lipid Peroxidation as a Mediator of Chemical-induced Hepatocyte Death Mario Comporti 8. Immunologic Meditation of Chemical-induced Hepatotoxicity Sylvia Furst Jay Gandolfi 9. The Role of Nonpharenchymal Cells and Inflammatory Macrophages in Hepatotoxicity Debra Laskin and Carol Gardner 10. Cholestatic Properties of Steroid Glucuronides Mary Vore and Kim Brouwer 11. Mechanisms Involved in Bile Acid-induced Cholestasis Ibrahim Yousef
Guylaine Bouchard
Beatriz Tuchweber and Gabriel Plaa 12. Cholestasis Produced by Combinations of Manganese and Bilirubin Gabriel Plaa
Alexandra Duguay
Lena King and William Hewitt 13. Evaluation of Chemical-induced Bile Duct Proliferation Claude Barriault
Alexis Desmouliere
Andrea Monte Alto Costa
Ibrahim Yousef and Beatriz Tuchweber. Guylaine Bouchard
University of Montreal
Canada
Kim Brouwer
University of North Carolina
USA
Steven Cohen
University of Connecticut
USA
Mario Comporti
University of Siena
Italy
Andrea Monte Alto Costa
Universidade do Estado do Rio de Janeiro
Brazil
Alexis Desmouliere
Institut de Biologie et Chimie des Proteines
France
Alexandra Duguay
University of Montreal
Canada
Patrick Eacho
Lilly Research Laboritories
USA
Sylvia Furst
Boehringer Ingelheim Pharmaceuticals
USA
Jay Gandolfi
University of Arizona
USA
Carol Gardner
Rutgers University
USA
William Hewitt
SmithKline Beecham Pharmaceuticals
USA
Debie Hoivik
Texas A&M University
USA
Edward Khairallah
Deceased
Lena King
Parke Davis Research Institute
Canada
James Klaunig
Indiana University School of Medicine
USA
Kyle Kolaja
Indiana University School of Medicine
USA
Debra Laskin
Rutgers University
USA
Jeffrey Lawrence
Merck Research Laboratories
USA
James Newberne
University of Cincinatti
USA
Paul Newberne
Boston University School of Medicine
USA
Gabriel Plaa
University of Montreal
Canada
Donald Reed
Oregan State University
USA
Beatriz Tuchweber
University of Montreal
Canada
Mary Vore
University of Kentucky
USA
Ibrahim Yousef
University of Montreal
Canada
Hyman Zimmerman
George Washington University
USA.