In recent years, heterocyclic compounds are one of the most exploring fields in heterocyclic chemistry due to their diverse biological importance. Among the heterocyclic compounds, nitrogen, sulphur, oxygen heterocycles play a vital role in our day to day life. Inspired by the extensive advances of molecular hybridization with their significance, indoloisoquinoline, pyrimidine, thiazole-2-amine compounds are associated legitimately or by implication to N-bridged heterocyclic thiazolidinone, azetidinone, pi-conjugated 1,3,4-oxadiazole and heteroaromatic indole analogs. In line with previous reports new compounds have the biological potential as antimicrobial, anticancer, anti-TB, antioxidant activities. Molecular docking further supports the theoretical data with clear display of binding of molecules with protein and its effect.
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