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Detection of the boundary of an object in medical images, then the segmentation from the background class, is a major challenge in medical image processing. Active Contour Model, or Snake, which is a deformable model for approaching object boundaries, it is a curve defined within an image domain which can move under the influence of internal forces from the curve itself and external forces from the image data ; That's mean using different energy function B-Snake (GVF(s)) is able not only to grow through long and thin concavities but also it does not miss the correct boundaries.