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Advanced Microbiology integrates multi-omics technologies-genomics, transcriptomics, proteomics, and metabolomics-with computational systems biology to decode microbial mechanisms and applications. It bridges molecular insights with industrial-environmental solutions, including waste remediation, agricultural optimization, and pharmaceutical innovation, while exploring frontiers like synthetic biology and space biotechnology. Featuring 200+ diagrams and case studies, the book equips researchers and bioengineers with advanced computational strategies and AI-driven tools to address sustainability challenges. Pedagogical elements foster critical analysis, positioning microbial systems as keys to ecological resilience and biotechnological breakthroughs. A concise yet comprehensive resource for advancing next-generation microbial research across academia and industry.