Advancing Constraint-Based Metabolic Modeling Approaches for Microbial Strain Design - Alter, Tobias
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This dissertation advances the use of metabolic models for designing industrially relevant microbial cell factories. At the same time, the presented theoretical results give valuable insights into the functioning and limitations of microbial metabolism. Thus, the application of model-based approaches in the biological sciences to make the most out of the available data for engineering and knowledge generation purposes is widely promoted.

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This dissertation advances the use of metabolic models for designing industrially relevant microbial cell factories. At the same time, the presented theoretical results give valuable insights into the functioning and limitations of microbial metabolism. Thus, the application of model-based approaches in the biological sciences to make the most out of the available data for engineering and knowledge generation purposes is widely promoted.