Andrew Hadley / Peter Soothill (eds.)

Alloimmune Disorders of Pregnancy

Herausgeber: Hadley, Andrew; Soothill, Peter

• Gebundenes Buch

Produktbeschreibung

Collectively known as the alloimmune cytopenias, hemolytic disease of the fetus and newborn, alloimmune thrombocytopenia and alloimmune neutropenia are all consequences of maternal immunisation to fetal blood cells. The effective prevention, diagnosis and management of these disorders has become a team effort involving haematologists, obstetricians, paediatricians, immunologists, laboratory technicians, midwives and research scientists. This book has been written by experts in their respective fields to bring together the issues of pathogenesis, epidemiology, prevention, diagnosis and clinical management. This comprehensive but accessible account is extensively cross-referenced to emphasise the links between pathogenesis and clinical sequelae, between epidemiology and the rationale for screening programmes, and between diagnosis and therapeutic intervention. This is an authoritative overview suitable for trainees in obstetrics, materno-fetal medicine, transfusion medicine and clinical immunology.

Produktdetails

• Verlag: Cambridge University Press
• Seitenzahl: 306
• Erscheinungstermin: 7. Januar 2015
• Englisch
• Abmessung: 250mm x 175mm x 21mm
• Gewicht: 710g
• ISBN-13: 9780521781206
• ISBN-10: 0521781205
• Artikelnr.: 21124558

Autorenporträt

Dr Andrew Hadley is Division Manager at the International Blood Group Reference Laboratory, and Senior Scientist at the Bristol Institute for Transfusion Sciences, University of Bristol.

Inhaltsangabe

Preface Andrew G. Hadley and Peter Soothill; 1. Pathophysiology of the
alloimmune cytopenias Andrew G. Hadley and Craig Turner; 2. Blood group
antibodies in haemolytic disease of the fetus and newborn Geoff Daniels; 3.
Basis and practice of screening for haemolytic disease of the fetus and
newborn Geoff Poole; 4. Epidemiology and screening for alloimmune
thrombocytopenia Lorna M. Williamson and Michael F. Murphy; 5. Principles
of antibody-mediated immune suppression and the prevention of maternal
Rh(D) alloimmunisation Belinda Kumpel; 6. The clinical application of
anti-D prophylaxis Stan Urbaniak; 7. Fetal genotyping Neil D. Avent; 8.
Laboratory assays to determine the severity of haemolytic disease of the
fetus and newborn Andrew G Hadley; 9. Assessing the severity of haemolytic
disease of the fetus and newborn: clinical aspects Sherif Abdel-Fattah and
Peter Soothill; 10. Antenatal therapy for haemolytic disease of the fetus
and newborn Kenneth J. Moise and Paul W. Whitecar; 11. Neonatal therapy for
haemolytic disease of the newborn Glynn Russell and Nic Goulden; 12. The
diagnosis of alloimmune thrombocytopenia Andrew Hadley; 13. The diagnosis
of alloimmune neutropenia Geoff Lucas; 14. Fetal and neonatal treatment of
alloimmune thrombocytopenia Michael Murphy, Rachel Rayment, David Allen and
David Roberts; Index.