Illustrations vii Foreword / Tim Lenoir xi Prologue 1 Part I. Historical Epistemology 1. Ludwik Fleck, Edmond Husserl: On the Historicity of Scientific Knowledge 13 2. Gaston Bachelard: The Concept of "Phenomenotechnique" 25 3. Georges Canguilhem: Epistemological History 37 Part II. Model Organisms: Studies in the History of Heredity and Reproduction 4. Pisum: Carl Carren's Experiments on Xenia, 1896-99 51 5. Eudorina: Max Hartmann's Experiments on Biological Regulation in Protozoa, 1914-21 82 6. Ephistia: Alfred Kühn's Experimental Design for a Developmental Physiological Genetics, 1924-45 94 7. Tobacco Mosaic Virus: Virus Research at the Kaiser Wilhelm Institutes for Biochemistry and Biology, 1937-45 128 Part III. Concepts and Instruments: Studies in the History of Molecular Biology 8. The Concept of the Gene: Molecular Biological Perspectives 153 9. The Liquid Scintillation Counter: Traces of Radioactivity 170 10. The Concept of Information 203 Part IV. Epistemic Configurations 11. Intersections 217 12. Preparations 233 13. The Economy of the Scribble 244 Acknowledgments 253 Abbreviations 255 Notes 257 Bibliography 289 Index 321
Illustrations vii Foreword / Tim Lenoir xi Prologue 1 Part I. Historical Epistemology 1. Ludwik Fleck, Edmond Husserl: On the Historicity of Scientific Knowledge 13 2. Gaston Bachelard: The Concept of "Phenomenotechnique" 25 3. Georges Canguilhem: Epistemological History 37 Part II. Model Organisms: Studies in the History of Heredity and Reproduction 4. Pisum: Carl Carren's Experiments on Xenia, 1896-99 51 5. Eudorina: Max Hartmann's Experiments on Biological Regulation in Protozoa, 1914-21 82 6. Ephistia: Alfred Kühn's Experimental Design for a Developmental Physiological Genetics, 1924-45 94 7. Tobacco Mosaic Virus: Virus Research at the Kaiser Wilhelm Institutes for Biochemistry and Biology, 1937-45 128 Part III. Concepts and Instruments: Studies in the History of Molecular Biology 8. The Concept of the Gene: Molecular Biological Perspectives 153 9. The Liquid Scintillation Counter: Traces of Radioactivity 170 10. The Concept of Information 203 Part IV. Epistemic Configurations 11. Intersections 217 12. Preparations 233 13. The Economy of the Scribble 244 Acknowledgments 253 Abbreviations 255 Notes 257 Bibliography 289 Index 321
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