Des Nicholl presents here a new, fully revised, and expanded edition of his popular undergraduate-level textbook. Many of the features of the original edition have been retained; the book still offers a concise technical introduction to the subject of genetic engineering. However, the book is now divided into three main sections: the first introduces students to basic molecular biology, the second section explains the methods used to manipulate genes, and the third deals with modern applications of genetic engineering. A whole chapter is now devoted to the polymerase chain reaction.…mehr
Des Nicholl presents here a new, fully revised, and expanded edition of his popular undergraduate-level textbook. Many of the features of the original edition have been retained; the book still offers a concise technical introduction to the subject of genetic engineering. However, the book is now divided into three main sections: the first introduces students to basic molecular biology, the second section explains the methods used to manipulate genes, and the third deals with modern applications of genetic engineering. A whole chapter is now devoted to the polymerase chain reaction. Applications covered in the book include genomics, protein engineering, gene therapy, cloning, and transgenic animals and plants. A final chapter discusses the ethical questions surrounding genetic engineering in general. An Introduction to Genetic Engineering is essential reading for undergraduate students of biotechnology, genetics, molecular biology and biochemistry.
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Autorenporträt
DESMOND NICHOLL is Senior Lecturer in the Department of Biological Sciences, The University of Paisley, Scotland
Inhaltsangabe
From the contents: Preface to the second edition 1. Introduction; Part I. The Basis of Genetic Engineering: 2. Introducing molecular biology 3. Working with nucleic acids 4. The tools of the trade; Part II. The Methodology of Gene Manipulation: 5. Host cells and vectors 6. Cloning strategies 7. The polymerase chain reaction 8. Selection, screening, and analysis of recombinants; Part III. Genetic Engineering in Action: 9. Understanding genes and genomes 10. Genetic engineering and biotechnology 11. Medical and forensic applications of gene manipulation 12. Transgenic plants and animals 13. The other sort of cloning 14. Brave new world or genetic nightmare?; Suggestions for further reading; Using the World Wide Web; Glossary; Index
Preface Part I. Genetic Engineering in Context: 1. Introduction 2. The story of DNA 3. Brave new world or genetic nightmare? Part II. The Basis of Genetic Engineering: 4. Introducing molecular biology 5. The tools of the trade 6. Working with nucleic acids Part III. The Methodology of Gene Manipulation: 7. Host cells and vectors 8. Cloning strategies 9. The polymerase chain reaction 10. Selection, screening and analysis of recombinants 11. Bioinformatics 12. Genome editing Part IV. Genetic Engineering in Action: 13. Investigating genes, genomes and 'otheromes' 14. Genetic engineering and biotechnology 15. Medical and forensic applications of gene manipulation 16. Transgenic plants and animals 17. The other sort of cloning Glossary Index.
From the contents: Preface to the second edition 1. Introduction; Part I. The Basis of Genetic Engineering: 2. Introducing molecular biology 3. Working with nucleic acids 4. The tools of the trade; Part II. The Methodology of Gene Manipulation: 5. Host cells and vectors 6. Cloning strategies 7. The polymerase chain reaction 8. Selection, screening, and analysis of recombinants; Part III. Genetic Engineering in Action: 9. Understanding genes and genomes 10. Genetic engineering and biotechnology 11. Medical and forensic applications of gene manipulation 12. Transgenic plants and animals 13. The other sort of cloning 14. Brave new world or genetic nightmare?; Suggestions for further reading; Using the World Wide Web; Glossary; Index
Preface Part I. Genetic Engineering in Context: 1. Introduction 2. The story of DNA 3. Brave new world or genetic nightmare? Part II. The Basis of Genetic Engineering: 4. Introducing molecular biology 5. The tools of the trade 6. Working with nucleic acids Part III. The Methodology of Gene Manipulation: 7. Host cells and vectors 8. Cloning strategies 9. The polymerase chain reaction 10. Selection, screening and analysis of recombinants 11. Bioinformatics 12. Genome editing Part IV. Genetic Engineering in Action: 13. Investigating genes, genomes and 'otheromes' 14. Genetic engineering and biotechnology 15. Medical and forensic applications of gene manipulation 16. Transgenic plants and animals 17. The other sort of cloning Glossary Index.
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