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L-asparaginase from plants origin leads to the death of leukaemic and tumor cells L-sparaginase consider an antineoplastic agent use as therapy to treat acute lymphoblastic leukemia and lymphoma. L-asparaginase is a therapeutically important protein use with other drugs in the treatment of acute lymphocytic leukemia, lymphosarcoma, melanosarcoma and different kinds of cancer L-asparaginase use to treat hepatocellular cell lines. L-asparaginase is a natural and inexpensive product and can rasy obtained from diet containing all or somre parts or organs of plants.