BIOANALYTICAL ESTIMATION OF IMIQUIMOD IN RABBIT PLASMA BY RP-HPLC - Pinnamaneni, Prachet
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The present study focuses on the identification and estimation of drugs in the biological matrix using a sophisticated analytical technique also studying their pharmacokinetic parameters like half-lives and rates of elimination and their metabolites in blood. Imiquimod topical treats external warts around the genital and rectal areas called condyloma acuminatum. A direct relationship exists between the drug concentration at the bio-phase (site of action) and the concentration of the drug in plasma. A typical plasma drug concentration-time curve obtained after a single oral dose of a drug and…mehr

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Produktbeschreibung
The present study focuses on the identification and estimation of drugs in the biological matrix using a sophisticated analytical technique also studying their pharmacokinetic parameters like half-lives and rates of elimination and their metabolites in blood. Imiquimod topical treats external warts around the genital and rectal areas called condyloma acuminatum. A direct relationship exists between the drug concentration at the bio-phase (site of action) and the concentration of the drug in plasma. A typical plasma drug concentration-time curve obtained after a single oral dose of a drug and showing various pharmacokinetic and pharmacodynamic parameters.
Autorenporträt
Prachet Pinnamaneni, an enthusiastic learner with hard work in seeking all the possibilities for knowledge and fulfilling societal needs through sound research. Currently working as Assistant professor in the Department of Pharmaceutical Analysis, Chalapathi Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh.