This volume draws together apparently disparate studies of the interaction of mechanical forces with a range of cell types derived from skeletal muscle, bone and cardiovascular tissue to provide a comprehensive synthesis and review of recent work in this exciting new field.
This volume draws together apparently disparate studies of the interaction of mechanical forces with a range of cell types derived from skeletal muscle, bone and cardiovascular tissue to provide a comprehensive synthesis and review of recent work in this exciting new field.
Preface Part I. Soft Tissue: 1. Signal transduction in vascular cells exposed to cyclic strain 2. Effects of pressure overload on vascular smooth muscle cells 3. Effect of increased flow on release of vasoactive substances from vascular endothelial cells 4. Modulation of endothelium derived relaxing factor activity by flow 5. Stretch, overload and gene expression in muscle 6. Stretch sensitivity in stretch receptor muscles 7. Mechanical interactions with plant cells - a selective overview 8. Mechanical tensing of cells and chromosome arrangement 9. Alterations in gene expression induced by low-frequency, low-intensity electromagnetic fields Part II. Hard Tissue: 10. Cellular modelling of mechanical interactions with the skeleton 11. Mechanical and hormonal influences in vivo cause regional differences in bone remodelling 12. Mechanically sensitive cells in bone 13. Mechanical stress and bone development 14. Applications of homogenous, defined strains to cell cultures 15. The role of prostaglandin in bone cells as mediators of mechanical strain 16. Effects of mechanical stretch on actin polymerisation in fibroblasts of the periodontium 17. Modulation of cartilage extracellular matrix turnover by pulsed electromagnetic fields Index.
Preface Part I. Soft Tissue: 1. Signal transduction in vascular cells exposed to cyclic strain 2. Effects of pressure overload on vascular smooth muscle cells 3. Effect of increased flow on release of vasoactive substances from vascular endothelial cells 4. Modulation of endothelium derived relaxing factor activity by flow 5. Stretch, overload and gene expression in muscle 6. Stretch sensitivity in stretch receptor muscles 7. Mechanical interactions with plant cells - a selective overview 8. Mechanical tensing of cells and chromosome arrangement 9. Alterations in gene expression induced by low-frequency, low-intensity electromagnetic fields Part II. Hard Tissue: 10. Cellular modelling of mechanical interactions with the skeleton 11. Mechanical and hormonal influences in vivo cause regional differences in bone remodelling 12. Mechanically sensitive cells in bone 13. Mechanical stress and bone development 14. Applications of homogenous, defined strains to cell cultures 15. The role of prostaglandin in bone cells as mediators of mechanical strain 16. Effects of mechanical stretch on actin polymerisation in fibroblasts of the periodontium 17. Modulation of cartilage extracellular matrix turnover by pulsed electromagnetic fields Index.
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