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The book covers some differences related to elevated BMI in the presentation of breast cancer as well as molecular aspect of epigenetics in BRCA1 gene. The lifestyle behavior, urbanization and upper SES, intake of junk food collectively enhances body weight and cell proliferation. Hypermethylation of BRCA1 gene was significantly associated with carcinoma of Breast. The book covers complete research overview on impact of life style as well as molecular aspect of BRCA1 gene (most aggressive) in carcinoma of breast.