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Akin to nitric oxide, carbon monoxide (CO) was initially viewed as a pure toxic gas, yet it has been recently demonstrated to be an important endogenous molecule of gas that has profound physiological and pathophysiological effects on the cardiovascular system. The first book dedicated to this subject, Carbon Monoxide and Cardiovascular Functions presents many never-before-published results including the first case of human CO deficiency. It also discusses disorders where the cardiovascular effects of CO might have been altered, including hypertension, diabetes, stroke, and ischemic heart damage.