Carcinogenesis and Protein Kinase C - Refaat, Eman;Ibrahim, Amr Mahmoud M. M.
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A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. PKC isozymes are activated by a variety of hormones, such as adrenalin and angiotensin, by growth factors, including epidermal growth factor and insulin, and by neurotransmitters such as dopamine and endorphin; these stimulators, when bound to their respective receptors, activate members of the…mehr

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Produktbeschreibung
A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. PKC isozymes are activated by a variety of hormones, such as adrenalin and angiotensin, by growth factors, including epidermal growth factor and insulin, and by neurotransmitters such as dopamine and endorphin; these stimulators, when bound to their respective receptors, activate members of the phospholipase C family, which generates diacylglycerol, a lipid derived second messenger.
Autorenporträt
Eman Refaat Youness, docteur en biochimie médicale, faculté de médecine, Centre national de recherche, Gizeh, Égypte. Expérimentée dans la conception expérimentale et la recherche clinique, elle a publié de nombreux articles internationaux et est membre de sociétés internationales. Réviseur dans de nombreuses revues internationales.