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The similarities in inflammatory, joint, diabetes mellitus, and neurological diseases, are the action of reverse command tapes in the heart. These ribbons work in stages, over many years; diabetes mellitus is the beginning, diabetic nephropathy the last stage. In the joints, we have ankylosing spondylitis, arthritis, arthrosis, lupus, and fibromyalgia. What differentiates one disease from another is only the evolutionary process, as can be observed in diabetes. These reverse ribbons are responsible for the Covid 19 pandemic, the microcephaly epidemic in Pernambuco Brazil, and all the neurological diseases. Its command center is in the heart, but there are other centers such as the cerebellum, the cervical spine in axis, and also in the thalamic region.