Cardioskeletal Myopathies in Children and Young Adults focuses on plaques that kill people in their 40's-50's and the way they start to form in young adulthood. The Annals of Family Medicine report that approximately half of young adults have at least one cardiovascular disease risk factor (Mar 2010), and an increase in cardiovascular mortality rates in young adults was substantiated in a study at Northwestern Medicine (Nov 2011). Given the increasing recognition of genetic triggers behind all types of cardiovascular disease, and the growing population of young adults with primary or…mehr
Cardioskeletal Myopathies in Children and Young Adults focuses on plaques that kill people in their 40's-50's and the way they start to form in young adulthood. The Annals of Family Medicine report that approximately half of young adults have at least one cardiovascular disease risk factor (Mar 2010), and an increase in cardiovascular mortality rates in young adults was substantiated in a study at Northwestern Medicine (Nov 2011).
Given the increasing recognition of genetic triggers behind all types of cardiovascular disease, and the growing population of young adults with primary or acquired myocardial disease, the need has arisen for a reference that offers a comprehensive approach to the understanding of basic, translational, and clinical aspects of specific muscle diseases while making the link between young adult and adult health.
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Autorenporträt
Dr. Jefferies is a recognized international expert in the field of heart muscle disease contributing much of the current literature regarding related genetic mechanisms, clinical investigation, and guideline development.
Inhaltsangabe
Section I. Physiology and Molecular Basis of Muscle
Chapter 1. Ventricular Systolic Function
Chapter 2. Basics of Skeletal Muscle Function and Normal Physiology
Chapter 3. Molecular Pathways in Cardiomyopathies
Chapter 4. Abnormal Muscle Pathology and Physiology
Section II. Diseases of Cardio-Skeletal Phenotypes
Chapter 5. Dilated Cardiomyopathy and Cardioskeletal Involvement
Chapter 6. Hypertrophic Cardiomyopathy
Chapter 7. Restrictive Cardiomyopathy Associated With Skeletal Myopathies
Chapter 8. Left Ventricular Noncompaction Cardiomyopathy
Chapter 9. Diseases of the Cytoskeleton: The Desminopathies
Chapter 10. Diseases of Cardiac Sarcomeres
Chapter 11. Diseases of the Intercalated Disc
Chapter 12. Diseases of the Nuclear Membrane
Section III. Metabolic Causes of Disease
Chapter 13. Mitochondrial Disorders Causing Cardioskeletal Myopathies in Childhood
"This comprehensive review includes numerous diagrams and illustrations of the molecular disruption, pathology, and various diagnostic modalities in these myopathies. This is an essential tool for researchers and clinicians involved in their research, diagnosis, and treatment. Score: 89 - 3 Stars" --Doody's
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