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This monograph is about one of the directions in organic chemistry production - acetylene chemistry. In part one acetylene catalytic reactions and activation mechanism, in part two hydrohalogenation of acetylene, in part three given hydration of acetylene, and in part four acetylation of acetylene is given. Moreover, in the monograph it is given information about vinyl chloride, chloroprene, acetaldehyde, acetone and vinyl acetate production technology. This monograph could be useful for master students, doctoral students, researchers and technical workers working on this area.