Combinatorial Biotechnology: Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications provides a comprehensive exploration of the methods used for synthesizing peptide, oligonucleotide, and oligosaccharide libraries. This book serves as an invaluable resource for researchers and professionals in the fields of protein engineering, molecular biology, peptide synthesis, and carbohydrate chemistry, as well as those working in drug discovery within the pharmaceutical industry. The book systematically presents the concepts of combinatorial biotechnology,…mehr
Combinatorial Biotechnology: Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications provides a comprehensive exploration of the methods used for synthesizing peptide, oligonucleotide, and oligosaccharide libraries. This book serves as an invaluable resource for researchers and professionals in the fields of protein engineering, molecular biology, peptide synthesis, and carbohydrate chemistry, as well as those working in drug discovery within the pharmaceutical industry. The book systematically presents the concepts of combinatorial biotechnology, detailing both solid phase and solution phase synthesis techniques, including modern biological methods such as in vitro and in vivo display libraries. Key topics include solid phase synthesis, parallel peptide synthesis, encoding technologies, deconvolution methods, and chemical and biological ligations. With chapters covering the chemical and biological synthesis of recombinant peptides and proteins, as well as the genetic reprogramming of the genetic code, this book offers a rich source of knowledge and practical guidance. The inclusion of advanced methods and illustrative examples makes it a unique and essential reference in the field. This book is an essential resource for undergraduate and postgraduate students in biochemical engineering, biotechnology, and biosciences, as well as industry professionals in R&D divisions. It equips readers with the latest techniques and applications in combinatorial biotechnology, addressing current challenges and advancing their research and development efforts.
Dr. Preeti Srivastava obtained PhD from Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Delhi in the area of corynebacterial plasmid biology. She did postdoctoral research work in the area of chromosome dynamics in Vibrio cholerae from Laboratory of Biochemistry and molecular biology, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, Maryland, USA. She has worked as Senior Scientist in Environmental Biotechnology Division, Indian Institute of Toxicology Research (CSIR), Lucknow before joining IIT Delhi in 2011. Currently, she is working as Professor, Department of Biochemical Engineering and Biotechnology, IIT Delhi. Her present research interest is in Bacterial genetics and Environmental Biotechnology. She has published several papers in Internationally reputed journals and proceedings of National and International conferences. She has been granted 4 patents and has filed three patent applications. She is the recipient of the prestigious Innovative Young Biotechnologist Award and TATA innovation fellowship from Department of Biotechnology, Ministry of Science and technology, Government of India.
