Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups…mehr
Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions. The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules.
Shehryar Hameed obtained his M.Phil. degree in Organic Chemistry from H.E.J Research Institute of Chemistry, the University of Karachi under the supervision of Prof. Dr. Khalid. M. Khan. He is currently a doctoral researcher at the H.E.J Research Institute of Chemistry, University of Karachi. His research is focused on the "Synthesis of Some Biologically Active Compounds and Developing New Synthetic Methodologies?. His research interests are the synthesis of versatile scaffolds such as substituted quinoxaline, 1,2,3-triazole, phenyl-3,4-dihydropyrimidin-2(1H)-one and pyran heterocyclic derivatives in search of potential therapeutic agents and their broad range of medicinal applications for the development of novel ¿-amylase, ¿-glucosidase, urease, and cholinesterase inhibitors. He has numerous publications to his credit in various reputed journals of high impact factor.
Inhaltsangabe
1. General introduction of coumarin 2. Synthesis and reactivity 3. Naturally occurring coumarins in the development of commercial drugs 4. Multi-targeted scaffold in medicinal chemistry: Potential anticancer agents 5. Role of coumarins in different infectious diseases 6. In the design and development of neurotherapeutics agents 7. Development as anti-inflammatory and anticoagulant agents 8. Potential in antidiabetic and antioxidant therapies 9. Coumarin-based metal complexes and polymers 10. Recent advances in applications of coumarins: A brief discussion on patents and activities, current status and perspectives
1. General introduction of coumarin 2. Synthesis and reactivity 3. Naturally occurring coumarins in the development of commercial drugs 4. Multi-targeted scaffold in medicinal chemistry: Potential anticancer agents 5. Role of coumarins in different infectious diseases 6. In the design and development of neurotherapeutics agents 7. Development as anti-inflammatory and anticoagulant agents 8. Potential in antidiabetic and antioxidant therapies 9. Coumarin-based metal complexes and polymers 10. Recent advances in applications of coumarins: A brief discussion on patents and activities, current status and perspectives
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