Computational Approaches for Understanding Dynamical Systems: Protein Folding and Assembly

Herausgegeben:Strodel, Birgit; Barz, Bogdan

• Gebundenes Buch

Produktbeschreibung

Computational Approaches for Understanding Dynamical Systems: Protein Folding and Assembly, Volume 170 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Pairwise-Additive and Polarizable Atomistic Force Fields for Molecular Dynamics Simulations of Proteins, Scale-consistent approach to the derivation of coarse-grained force fields for simulating structure, dynamics, and thermodynamics of biopolymers, Enhanced sampling and free energy methods, and much more.

Produktdetails

• Progress in Molecular Biology and Translational Science Volume 170
• Verlag: Academic Press / Elsevier Science & Technology
• Artikelnr. des Verlages: S1877-1173(20)X0003-2
• Englisch
• Abmessung: 29mm x 152mm x 229mm
• Gewicht: 1000g
• ISBN-13: 9780128211359
• Artikelnr.: 67579546

Autorenporträt

Birgit Strodel studied chemistry at Heinrich Heine University Düsseldorf (Germany) and the University of North Carolina at Chapel Hill (USA) and received her PhD in Theoretical Chemistry from the University of Frankfurt/Main (Germany) in 2005. She then joined the group of Prof. David J. Wales at Cambridge University (UK) as a postdoctoral research associate. Since 2009 she heads the Computational Biochemistry Group at the Jülich Research Centre (Germany) and was appointed Professor at Heinrich Heine University Düsseldorf in 2011. Her research interests primarily involve the thermodynamics and kinetics of protein aggregation.

Inhaltsangabe

1. Pairwise-Additive and Polarizable Atomistic Force Fields for Molecular Dynamics Simulations of Proteins
Justin Lemkul
2. Scale-consistent approach to the derivation of coarse-grained force fields for simulating structure, dynamics, and thermodynamics of biopolymers
Adam Liwo
3. Monte Carlo methods in protein folding and assembly
Sandipan Mohanty
4. Enhanced sampling and free energy methods
Qinghua Liao
5. Markov models of molecular simulations of protein folding, protein-protein interactions, and aggregation
Nicolae-viorel Buchete
6. Molecular dynamics simulations with experimental restraints
Kresten Lindorff-Larsen
7. Protein folding simulations
Ivan Coluzza
8. Thermal stability of proteins
Fabio Sterpone
9. Aggregation of short disease-related peptides
Philippe Derreumaux
10. Dichotomy between universality and specificity of amyloid ?-protein oligomer formation: Molecular dynamics perspective
Brigita Urbanc
11. Computational studies of protein aggregation mediated by amyloid: Fibril elongation and secondary nucleation
Wei Han

Rezensionen

"This book is an excellent resource on computational approaches for understanding protein folding and assembly. Computational researchers, curious experimentalists, students, molecular biologists, and protein chemists will find it quite interesting. There are very few books available that go to such depths to explain computational approaches for understanding dynamical systems such as protein folding and assembly." --Doody