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This book introduces the essential principles of Geomedicine, an emerging field that links human health with geographic, environmental, and territorial conditions. Through a transdisciplinary approach, it explores the conceptual foundations that explain how space, climate, the built environment, and social determinants influence health and disease processes. The book offers a clear theoretical basis for understanding the spatial dimension of health phenomena, proposing useful analytical tools for public health research, planning, and intervention. It is aimed at health professionals, geographers, epidemiologists, environmentalists, and decision-makers interested in integrating territory as an essential variable in addressing health.