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Today, due to the rapid development of the chemical and pharmaceutical industry in the world and the growth of all branches of pharmaceutical production, the need for accurate and simple methods for the analysis of drug potency is increasing year by year. Therefore, special attention is paid to the development of rapid, simple and economically viable methods suitable for screening drug compounds. Ion-selective electrodes with plasticized membranes are a solution to this problem. Such electrodes are easy to manufacture, easy to manufacture and have a wide concentration range of the device. Therefore, it is important to develop a new generation of electroactive materials and develop selective electrodes that provide the development of drugs based on them. Currently, the world is actively developing high-performance electrode materials for ion-selective electrodes. The characteristics of ionselective electrodes are: high sensitivity in the flow and dependence on the composition of electroactive materials. Therefore, the production of ion-selective electrodes is an important task, which is to achieve the optimal composition and ratio of electroactive materials components in the output.