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Periodontitis is caused by inflammatory processes initiated by bacteria that colonize as oral biofilms (dental plaque) on teeth resulting in tissue destruction which manifests as gingival pockets, periodontal ligament destruction, and loss of tooth supporting alveolar bone. Concerning various aspects of periodontology such as diagnosis, etiopathogenesis, treatment, clinical research and future directions, there exist dilemma regarding the previous and latest information. This dilemma leads to emergence of critical issues.