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This comprehensive guide explores the intricate relationship between diabetes mellitus and dental implant therapy. It presents current evidence, clinical protocols, and outcome assessments for implant placement in both controlled and uncontrolled diabetic patients. Topics covered include the pathophysiology of diabetes affecting osseointegration, pre-surgical considerations, risk factors, implant survival rates, and post-operative care. Designed for dental professionals and postgraduate students, this book offers practical insights and evidence-based strategies to enhance implant success in diabetic individuals, bridging the gap between systemic health and oral rehabilitation.