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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Energy charge is an index used to measure the energy status of biological cells. It is related to ATP and ADP concentrations and its value effects rates of metabolism. Many reactions in metabolism are controlled by the energy status of the cell. One index of the energy status is the energy charge, which is proportional to the mole fraction of ATP plus half the mole fraction of ADP, given that ATP contains two anhydride bonds whereas ADP contains one.