Dental adhesive systems have undergone significant advancements, evolving from low-strength, and unstable first-generation materials to today's highly versatile universal adhesives. Enamel bonding is well-established using phosphoric acid etching, which creates micromechanical retention through resin tag formation. Dentin bonding, however, remains more complex due to its organic composition, tubular structure, and moisture sensitivity. The smear layer plays a crucial role, and its treatment ranging from removal to modification greatly affects bonding outcomes.The fourth-generation "total-etch" systems marked a major improvement in long-term dentin adhesion, while later generations aimed to simplify application steps. Self-etch adhesives introduced chemical bonding potential, particularly in dentin, though they often struggle with enamel. Universal adhesives (eighth generation) offer flexibility, combining the benefits of etch-and-rinse and self-etch approaches. Adhesive performance is influenced by factors like monomer composition, solvent systems, and hybrid layer quality.Despite simplification efforts, technique sensitivity and moisture control remain critical for success.
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