Andere Kunden interessierten sich auch für
![Design, Development of Nitrendipin Self-Microemulsifying Drug Delivery]( "Design, Development of Nitrendipin Self-Microemulsifying Drug Delivery")
Design, Development of Nitrendipin Self-Microemulsifying Drug Delivery29,99 €![Self Microemulsifying Drug Delivery System For Some Drugs]( "Self Microemulsifying Drug Delivery System For Some Drugs")
Self Microemulsifying Drug Delivery System For Some Drugs55,99 €![Formulation & Evaluation of Self Micro Emulsifying Drug Delivery]( "Formulation & Evaluation of Self Micro Emulsifying Drug Delivery")
Formulation & Evaluation of Self Micro Emulsifying Drug Delivery41,99 €![Development of Self Microemulsifying Drug Delivery System]( "Development of Self Microemulsifying Drug Delivery System")
Development of Self Microemulsifying Drug Delivery System33,99 €![Current and Future Potential of Gastroretentive Drug Delivery System]( "Current and Future Potential of Gastroretentive Drug Delivery System")
Current and Future Potential of Gastroretentive Drug Delivery System29,99 €![Nanotechnology as a versatile tool for enhancing drugs bioavailability]( "Nanotechnology as a versatile tool for enhancing drugs bioavailability")
Nanotechnology as a versatile tool for enhancing drugs bioavailability25,99 €![Nanosuspension Formulation Concerns]( "Nanosuspension Formulation Concerns")
Nanosuspension Formulation Concerns36,99 €
In this book, a method to prepare self-microemulsifying drug delivery system (SMEDDS) of the poorly water-soluble drugcefadroxil monohydrate is explained. The impact of the oil, surfactant and co-surfactant on the drug solubility and their ratios on forming efficient and stable SMEDDS were examined. Water titration method was used to formulation of SMEDDS. The SMEDDS were characterized by morphological observation, globule size, cloud point measurement,viscosity determination,refractive index,% transmittance, drug content of SMEDDS of cefadroxil monohydrate and in vitro release study. The optimum formulation F2 consisted of oleic acid, tween-80 and PEG-400 with S mix. ratio of 1:1. In vitro release test showed a complete release of cefadroxil monohydrate from SMEDDS in an approximately 1.5hr. SMEDDS cefadroxil monohydrate oral formulations were prepared that provide excellent drug solubilization and improved in vitro release of cefadroxil monohydrate compare to marked product. The selected formulation F2 was tested for pharmacokinetic studies in comparison to marketed formulation it showed increase in the oral bioavailability of cefadroxil monohydrate.