Exploring topics at the forefront of current lipid research, this book provides an introduction to functional lipidomics. With the help of an international panel of contributors, the editors capture the first snapshot of the current state of the art. Using both academic and industrial perspectives, the book supplies a comprehensive background for scientists new to the field and a resource for developing didactic courses in lipid cell signaling and lipid bioinformatics. It covers lipid analysis approaches, diagnostics using lipid and lipid-binding protein patterns, and the therapeutic…mehr
Exploring topics at the forefront of current lipid research, this book provides an introduction to functional lipidomics. With the help of an international panel of contributors, the editors capture the first snapshot of the current state of the art. Using both academic and industrial perspectives, the book supplies a comprehensive background for scientists new to the field and a resource for developing didactic courses in lipid cell signaling and lipid bioinformatics. It covers lipid analysis approaches, diagnostics using lipid and lipid-binding protein patterns, and the therapeutic significance in targeting proteins involved with the lipid signaling pathway.
The LIPID MAPS Approach to Lipidomics. LC/MS Methodology in Lipid Analysis and Structural Characterization of Novel Lipid Species. Functional Plasticity of Lipid Mediators: The Example of Endocannabinoids. Eicosanoid Lipidomics. Functional Lipidomics: Lysophosphatidic Acid as a Target for Molecular Diagnosis and Therapy of Ovarian Cancer. Analysis of Lysophospholipids in Human Body Fluids: Comparison of the Lysophospholipid Content in Malignant vs. Nonmalignant Diseases. Functional Lipidomics: Lessons and Examples from the Sphingolipids. Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Analysis of Sphingolipids. Methods of Probing Phosphoinositides-Protein Interactions. Fishing for Pharmaceutically Relevant phosphoinositide-Binding Proteins Using Chemical Proteomics. Phosphoinositide Pröling in Complex Lipid Mixtures. Multiplexed Lipid Arrays of Antiimmunoglobulin M-Induced Changes in the Glycerophospholipid Composition of WEHI-231 Cells. Speci¿c Lipid Alterations in Alzheimer's Disease and Diabetes: Shotgun Global Cellular Lipidome Analyses by Electrospray Ionization Mass Spectrometry Using Intrasource Separation. High-Throughput Lipid Pröling to Identify and Characterize Genes Involved in Lipid Metabolism, Signaling, and Stress Response.
The LIPID MAPS Approach to Lipidomics. LC/MS Methodology in Lipid Analysis and Structural Characterization of Novel Lipid Species. Functional Plasticity of Lipid Mediators: The Example of Endocannabinoids. Eicosanoid Lipidomics. Functional Lipidomics: Lysophosphatidic Acid as a Target for Molecular Diagnosis and Therapy of Ovarian Cancer. Analysis of Lysophospholipids in Human Body Fluids: Comparison of the Lysophospholipid Content in Malignant vs. Nonmalignant Diseases. Functional Lipidomics: Lessons and Examples from the Sphingolipids. Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Analysis of Sphingolipids. Methods of Probing Phosphoinositides-Protein Interactions. Fishing for Pharmaceutically Relevant phosphoinositide-Binding Proteins Using Chemical Proteomics. Phosphoinositide Pröling in Complex Lipid Mixtures. Multiplexed Lipid Arrays of Antiimmunoglobulin M-Induced Changes in the Glycerophospholipid Composition of WEHI-231 Cells. Speci¿c Lipid Alterations in Alzheimer's Disease and Diabetes: Shotgun Global Cellular Lipidome Analyses by Electrospray Ionization Mass Spectrometry Using Intrasource Separation. High-Throughput Lipid Pröling to Identify and Characterize Genes Involved in Lipid Metabolism, Signaling, and Stress Response.
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