Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. …mehr
Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data.
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Autorenporträt
Dr. Schmitt-Kopplin's research team performs tailored and comprehensive metabolomics in health and environment. He has a strong profile in analytical chemistry with integrated approaches combining (ultra)high resolution mass spectrometry, separation sciences, NMR-spectroscopy and bioinformatics for the description of complex molecular systems on a molecular level. His focus in the last decade was to implement ion cyclotron resonance Fourier transform mass spectrometry into applications for a rapid and robust tool for deep metabotyping and small molecules profiling. His interdisciplinary studies are related to important diseases linked to environmental factors and microbiome engineering such as in diabetes, asthma and allergies, probiotics, intestinal infections, and microbial pathogens.
Inhaltsangabe
Historical Chapters 1. Historical Developments in FTICRMS
Fundamental/Technology Chapters 2. Fundamentals of Orbitrap 3. Latest developments in FT-ICR-MS 4. Fundamentals and simulations in FT-ICR-MS 5. Advanced Fundamentals 6. Data processing & Automation in ICR-FT-MS 7. Fundamentals of 2D-FTMS 8. Ion Mobility and FTMS 9. Imaging FTMS 10. Laser Desorption Ionisation FT-ICR-MS
Applications Chapters 11. LC-MS Metabolomics in Orbitrap 12. Visualizing metabolic hypotheses on FT-ICR-MS 13. Environmental Chemistry/Organohalogens and FTMS 14. Bioactive Peptides 15. Forensic studies FTMS/Orbitrap 16. Petroleomics Orbitrap/FTMS 17. Proteomics/PTM Orbi/ICR 18. Gas Phase Ion-Molecule Reactions / Inorganics 19. Clusters Chemistry and Cold ICR-FTMS 20. Application of FTMS to the Analysis of Glycosaminoglycans 21. Foodomics in FTMS
Historical Chapters 1. Historical Developments in FTICRMS
Fundamental/Technology Chapters 2. Fundamentals of Orbitrap 3. Latest developments in FT-ICR-MS 4. Fundamentals and simulations in FT-ICR-MS 5. Advanced Fundamentals 6. Data processing & Automation in ICR-FT-MS 7. Fundamentals of 2D-FTMS 8. Ion Mobility and FTMS 9. Imaging FTMS 10. Laser Desorption Ionisation FT-ICR-MS
Applications Chapters 11. LC-MS Metabolomics in Orbitrap 12. Visualizing metabolic hypotheses on FT-ICR-MS 13. Environmental Chemistry/Organohalogens and FTMS 14. Bioactive Peptides 15. Forensic studies FTMS/Orbitrap 16. Petroleomics Orbitrap/FTMS 17. Proteomics/PTM Orbi/ICR 18. Gas Phase Ion-Molecule Reactions / Inorganics 19. Clusters Chemistry and Cold ICR-FTMS 20. Application of FTMS to the Analysis of Glycosaminoglycans 21. Foodomics in FTMS
Rezensionen
"Apart from this book that, at its time, provided a well-balanced introduction and state-of-the-art overview, there are only books containing single chapters on FT-ICR-MS or Orbitrap-MS. Overall, this book deserves a place on the bookshelves not only of academic libraries but even more so in MS laboratories using FT-based instrumentation. This review rates it at four of five stars." --Analytical and Bioanalytical Chemistry
"Basically, this monograph is well-structured and the assignment of the chapters into Sections A to C provides orientation for the reader. Generally, the authors have taken great care to provide well prepared and informative chapters each contributing to the whole package offered by this book." --Analytical and Bioanalytical Chemistry
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