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Four experiments were conducted on the growth response, nutrient utilization and laying pattern of pullets fed cassava peel meal (CPM) diet supplemented with cashew nut reject meal (CNM). Experiment 1 studied the protein quality of CPM and CNM using 12 male albino rats of the Wistar strain for 14 days. There were 4 diets: a basal diet, reference (casein) diet, CNM and CPM diets, allocated to 3 rats in each dietary treatment group. The data obtained were subjected to analysis of variance in a completely randomized design. In experiment 2, four hundred and thirty-two, 7 days old Yaafa brown pullet chicks were divided into 12 treatments with 3 replications of 12 birds each and fed for 56 days. The growth response, body temperature and blood constituents of growing pullets from experiment 2 were studied in experiment 3 for 13 weeks. Experiment 4 studied the growth response, body temperature, egg-laying performance and blood constituents of two hundred and eighty-eight Yaafa brown layers selected randomly from experiment 3 divided into 12 treatments with 3 replications of 8 birds each maintained in cage for 40 weeks on layers diets. A 10 % CPM and up to 30 % CNM was recommended.