The Handbook of Parkinson’s Disease Mechanisms offers an integrated overview of the fundamental research devoted to understanding its causes and mechanisms, highlighting recent advances and clinical significance.¿With a strong focus on cellular and animal model studies, this book also examines the etiology, pathophysiology, epidemiology and underlying symptoms of Parkinson’s disease. Written with an interdisciplinary approach, this book provides thorough research that will be of interest to researchers, clinicians and graduate students interested in neurodegenerative diseases.
The Handbook of Parkinson’s Disease Mechanisms offers an integrated overview of the fundamental research devoted to understanding its causes and mechanisms, highlighting recent advances and clinical significance.¿With a strong focus on cellular and animal model studies, this book also examines the etiology, pathophysiology, epidemiology and underlying symptoms of Parkinson’s disease. Written with an interdisciplinary approach, this book provides thorough research that will be of interest to researchers, clinicians and graduate students interested in neurodegenerative diseases.
1. Pathology, postmortem studies, neuromelanin 2. PD epidemiology and PD economic burden 3. Genetic influences and other causes 4. Animal models for the study of PD etiology 5. New cellular and organoid models for the study of PD 6. Lewy bodies, Molecular Interactions of Lewy bodies in the brain 7. Synaptophaty in PD; alpha-syn and tau relationship with PD 8. Parkinson's disease as a synucleinopathy 9. Lysosomal function and protein aggregation in PD 10. Autophagy and mitophagy and neuropathological markers of familiar PD 11. Mitochondrial dysfunction in PD 12. The gut brain axis in PD 13. Dopaminergic neurons susceptibility to degeneration / dysfunction of mitochondria, new PD models 14. Neuroinflammation and microglia 15. Extracellular space modifications and PD 16. Dopamine neurotransmission in Parkinson’s Disease 17. Dopamine effects in striatal and subthalamic nucleus neurons 18. Adaptations that follow partial and severe striatal dopaminergic denervation 19. Molecular mechanisms underlying L-DOPA-induced dyskinesia, role of dopamine receptors 20. Imaging and electrophysiology of direct and indirect pathway neurons in freely moving animals 21. Striatal cholinergic system in PD 22. Striatal serotoninergic system in PD 23. Opto and chemogenetic studies on L-DOPA-induced dyskinesia 24. Network dynamics in rodent PD and LID models 25. Network dynamics in primate models and patients ; effects of DBS on network dynamics 26. Mechanisms underlying impulse control disorders in PD 27. Brain stem mechanism of PD symptoms
1. Pathology, postmortem studies, neuromelanin 2. PD epidemiology and PD economic burden 3. Genetic influences and other causes 4. Animal models for the study of PD etiology 5. New cellular and organoid models for the study of PD 6. Lewy bodies, Molecular Interactions of Lewy bodies in the brain 7. Synaptophaty in PD; alpha-syn and tau relationship with PD 8. Parkinson's disease as a synucleinopathy 9. Lysosomal function and protein aggregation in PD 10. Autophagy and mitophagy and neuropathological markers of familiar PD 11. Mitochondrial dysfunction in PD 12. The gut brain axis in PD 13. Dopaminergic neurons susceptibility to degeneration / dysfunction of mitochondria, new PD models 14. Neuroinflammation and microglia 15. Extracellular space modifications and PD 16. Dopamine neurotransmission in Parkinson’s Disease 17. Dopamine effects in striatal and subthalamic nucleus neurons 18. Adaptations that follow partial and severe striatal dopaminergic denervation 19. Molecular mechanisms underlying L-DOPA-induced dyskinesia, role of dopamine receptors 20. Imaging and electrophysiology of direct and indirect pathway neurons in freely moving animals 21. Striatal cholinergic system in PD 22. Striatal serotoninergic system in PD 23. Opto and chemogenetic studies on L-DOPA-induced dyskinesia 24. Network dynamics in rodent PD and LID models 25. Network dynamics in primate models and patients ; effects of DBS on network dynamics 26. Mechanisms underlying impulse control disorders in PD 27. Brain stem mechanism of PD symptoms
Es gelten unsere Allgemeinen Geschäftsbedingungen: www.buecher.de/agb
Impressum
www.buecher.de ist ein Internetauftritt der buecher.de internetstores GmbH
Geschäftsführung: Monica Sawhney | Roland Kölbl | Günter Hilger
Sitz der Gesellschaft: Batheyer Straße 115 - 117, 58099 Hagen
Postanschrift: Bürgermeister-Wegele-Str. 12, 86167 Augsburg
Amtsgericht Hagen HRB 13257
Steuernummer: 321/5800/1497
USt-IdNr: DE450055826
