Today, human genetics is for everyone. It is about variation more than about illnesses, and increasingly about the common rather than about the rare. Once an obscure science or an occasional explanation for an odd collection of symptoms, human genetics is now part of everyday conversation. By coming to know genetic backgrounds, people can control their environments in more healthy ways. Genetic knowledge is, therefore, both informative and empowering. This edition of Human Genetics: Concepts and Applications shows students how and why that is true. Users who purchase Connect receive access to the full online eBook version of the textbook.…mehr
Today, human genetics is for everyone. It is about variation more than about illnesses, and increasingly about the common rather than about the rare. Once an obscure science or an occasional explanation for an odd collection of symptoms, human genetics is now part of everyday conversation. By coming to know genetic backgrounds, people can control their environments in more healthy ways. Genetic knowledge is, therefore, both informative and empowering. This edition of Human Genetics: Concepts and Applications shows students how and why that is true. Users who purchase Connect receive access to the full online eBook version of the textbook.
Ricki Lewiss career communicating science began with earning a Ph.D. in Genetics from Indiana University in 1980. It quickly blossomed into writing for newspapers and magazines and writing the introductory textbook Life. Since then, she has taught a variety of life science courses and has authored the textbook Human Genetics: Concepts and Applications and books about gene therapy, stem cells, and scientific discovery. She is a genetic counselor for a large medical practice, teaches a graduate online course in "Genethics" at Albany Medical College, and writes for Medscape Medical News, Genetic Literacy Project, Rare Disease Report, and medical journals. Ricki also writes the popular DNA Science blog at Public Library of Science and is a frequent public speaker.
Inhaltsangabe
Human Genetics, 9e Part 1 Introduction Chapter 1Overview of Genetics Chapter 2Cells Chapter 3 Meiosis and DevelopmentPart 2 Transmission Genetics Chapter 4 Single-Gene Inheritance Chapter 5Beyond Mendel's Laws Chapter 6Matters of Sex Chapter 7 Multifactorial Traits Chapter 8Genetics of BehaviorPart 3 DNA and Chromosomes Chapter 9DNA Structure and Replication Chapter 10 Gene Action: From DNA to Protein Chapter 11Gene Expression and Epigenetics Chapter 12Gene Mutation Chapter 13Chromosomes Part 4 Population Genetics Chapter 14Constant Allele Frequencies Chapter 15Changing Allele Frequencies Chapter 16 Human Ancestry Part 5 Immunity and Cancer Chapter 17Genetics of Immunity Chapter 18Genetics of Cancer Part 6 Genetic Technology Chapter 19Genetic Technologies: Amplifying, Modifying, and Monitoring DNA Chapter 20Genetic Testing and Treatment Chapter 21Reproductive Technologies Chapter 22Genomics
List of Figures & Tables
Acknowledgements
Abbreviations
Chapter 1. From Mendel's Peas to Double Helices
From Genes to Genomes
Agriculture is Applied Genetics
Mendel's Experiments -The Mystery of the Missing Traits
The Chromosome Connection
In Pursuit of the Genetic Material
Chapter 2. How Genes Work
A Brief History of CF
Mikayla's Story
The Individual Level: Tissues and Organs
The Family Level
The Population
Chapter 3. Genes and Health
A Genomic View of Health
Causes of Death - An Organizing Framework
Cancer: The Cell Cycle Out of Control
The Microbiome and Infectious Disease
Chapter 4. Genetic Testing
The First Generation of Genetic Tests: Proteins
The Second Generation of Genetic Tests: DNA
The Third Generation of Genetic Tests: Exomes and Genomes
Human Genetics, 9e Part 1 Introduction Chapter 1Overview of Genetics Chapter 2Cells Chapter 3 Meiosis and DevelopmentPart 2 Transmission Genetics Chapter 4 Single-Gene Inheritance Chapter 5Beyond Mendel's Laws Chapter 6Matters of Sex Chapter 7 Multifactorial Traits Chapter 8Genetics of BehaviorPart 3 DNA and Chromosomes Chapter 9DNA Structure and Replication Chapter 10 Gene Action: From DNA to Protein Chapter 11Gene Expression and Epigenetics Chapter 12Gene Mutation Chapter 13Chromosomes Part 4 Population Genetics Chapter 14Constant Allele Frequencies Chapter 15Changing Allele Frequencies Chapter 16 Human Ancestry Part 5 Immunity and Cancer Chapter 17Genetics of Immunity Chapter 18Genetics of Cancer Part 6 Genetic Technology Chapter 19Genetic Technologies: Amplifying, Modifying, and Monitoring DNA Chapter 20Genetic Testing and Treatment Chapter 21Reproductive Technologies Chapter 22Genomics
List of Figures & Tables
Acknowledgements
Abbreviations
Chapter 1. From Mendel's Peas to Double Helices
From Genes to Genomes
Agriculture is Applied Genetics
Mendel's Experiments -The Mystery of the Missing Traits
The Chromosome Connection
In Pursuit of the Genetic Material
Chapter 2. How Genes Work
A Brief History of CF
Mikayla's Story
The Individual Level: Tissues and Organs
The Family Level
The Population
Chapter 3. Genes and Health
A Genomic View of Health
Causes of Death - An Organizing Framework
Cancer: The Cell Cycle Out of Control
The Microbiome and Infectious Disease
Chapter 4. Genetic Testing
The First Generation of Genetic Tests: Proteins
The Second Generation of Genetic Tests: DNA
The Third Generation of Genetic Tests: Exomes and Genomes
Chapter 5. Gene Therapy and Genome Editing
Protein Therapy Came First
Gene Therapy
Gene and Genome Editing
Chapter 6. From Ancestry to Destiny
DNA as Clock and Compass
The First Hominins
DNA Evidence Overlaps Fossil Evidence
Expansion Out of Africa
From Archaic Humans to Modern Humans
Into Europe
Genetic Genealogy and Ancestry Testing
The Future: Will Humanity Homogenize or Diverge?
Glossary
Bibliography
Index
Rezensionen
"A fascinating and informative introduction to the topic of human genetics. This excellent book would be suitable for anyone wishing to obtain a better understanding of genetic topics, especially those related to human health and disease." Elaine Hemers, Liverpool John Moores University, UK
The second edition of this excellent book gives a comprehensive overview of the expanding field of human genetics. Easy to read and illustrated with real life examples the book is enjoyable to read for everyone interested in human genetics, both lay persons and professionals. Katarina Pelin, University of Helsinki, Finland
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