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Potential predictors of death in covid-19 patients were advanced age, hypertension, and diabetes mellitus through hyperglycemia, which is a severity factor influencing death. The aim was to contribute to improving the management of hyperglycemic covid-19 patients. This is a retrospective cohort study carried out in the CTCOs of Lubumbashi. Patients were collected according to inclusion criteria. For each patient included, information was collected using a pre-established form. Statistical analyses were performed using IBM SPSS software. Survival was defined as the probability of an event occurring at each point in time. Hyperglycemia and mortality were associated 3 times for age between 40-59 years (HRa2.44(1.42-4.18), <0.001), 3 times for age 60 years (HRa2.83(1.69-4.76), <0.001); 2-fold for SaO2 <90% (HRa1.51(1.07-3.38) <0.001) and 3-fold for severe covid-19 (HRa3.04(1.56-5.92), <0.001). Hyperglycemia and mortality appear to be associated with advanced age, SaO2<90%, severe form of covid-19 and smoking.