Immunoprotection of mice immunised with Recombinant Oligopeptidase B - Sarah, Nanyiti;Boulange, Alain;Lubega, George William
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Development of a vaccine for trypanosomiasis has been challenged by the presence of antigenic variation in trypanosomes. This work circumvents the challenge of antigenic variation by using alternative vaccine targets wwhich are conserved . Here the serine ooligopeptidase protein of trypanasomes is used as a possible protein for use in deveopment of a vaccine for trypanosomiasis. The results show that the oligopeptidase B has a potenntial for protection but this needs further confirmation by using the protein in association with other potential vaccine targets.

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Produktbeschreibung
Development of a vaccine for trypanosomiasis has been challenged by the presence of antigenic variation in trypanosomes. This work circumvents the challenge of antigenic variation by using alternative vaccine targets wwhich are conserved . Here the serine ooligopeptidase protein of trypanasomes is used as a possible protein for use in deveopment of a vaccine for trypanosomiasis. The results show that the oligopeptidase B has a potenntial for protection but this needs further confirmation by using the protein in association with other potential vaccine targets.
Autorenporträt
I am an upcoming young scientist who is interested in building a scientific career. My research interests are biased towards molecular biology and biochemistry. I have experience in molecular biology and biotechnology skills that i havew developed over a qiperiod of 7 years.